HECTYL - Références Scientifiques & Réglementaires

BIBLIOGRAPHIE COMPLETE

Dans le cadre de la conception et de la formulation de ses produits nutri-cosmétiques haut de gamme, Hectyl s’engage à garantir la transparence et la véracité de ses allégations. Les produits de la JVCE ® FORMULA intègrent des ingrédients brevetés et des composants rigoureusement sélectionnés pour leurs bienfaits scientifiquement prouvés sur la santé et la beauté.

Afin de soutenir ces allégations et d’assurer une information fiable et précise, Hectyl a rassemblé une collection d’études scientifiques officielles, consultables en ligne. Cette bibliographie regroupe des recherches et publications qui valident l’efficacité et la sécurité des ingrédients utilisés dans les formules Hectyl. Chaque référence a été choisie pour son sérieux académique et son apport significatif aux connaissances dans le domaine de la nutri-cosmétique.

Les études incluses dans cette bibliographie abordent divers aspects, notamment :

  • les mécanismes d’action des ingrédients ;
  • les résultats des essais cliniques ;
  • les bénéfices pour la peau et la santé globale.

Avec cette documentation, Hectyl souhaite offrir à ses clients et partenaires une compréhension approfondie des bases scientifiques sur lesquelles repose la JVCE ® FORMULA et renforcer leur confiance dans l’excellence de ses produits.

INGREDIENTS BREVETES

RiaGev-WS™

1. Hellsten Y, L Skadhauge, J Bangsbo. Effect of Ribose Supplementation on Resynthesis of Adenine Nucleotides after Intermittent Training in Humans, Am J Physiol Regul Integr Comp Physiol; 286:R182-R188 (2004).
2. Berardi, J.M., and T.N. Ziegenfuss. Effects of ribose supplementation on repeated sprint performance in men. J. Strength Cond. Res. 17(1):47–52. (2003).
3. Falk, D.J., K.A. Heelan, J.P. Thyfault, and A.J. Koch. Effects of effervescent creatine, ribose, and glutamine supplementation on muscular strength,muscular endurance, and body composition. J. Strength Cond. Res. 17(4):810–816. (2003).
4. Darin Van Gammeren, MAEd, CSCS, Darin Falk, MAEd and Jose Antonia, PhD, The Effect of Four Weeks of Ribose Supplementation on Body Composition and Exercise Performance in Healthy, Young, Male Recreational Bodybuilders : A Double-Blind Placebo-Controlled Trial, Curr Ther Clin Exp. 63:486-195 (2002).
5. M. Gross, B.Kormann, and N.Zöllner. Klin Wochenschr 69:151-155 (1991).
6. Joanne S. Ingwall, PhD. On the Hypothesis that the Failing Heart Is Energy Starved : Lesson Learned from the Metabolism of ATP and Creatine, Current Hypertension Reports, 8:457-464 (2006).
7. Jacob Teitelbaum, Janelle Jandrain and Ryan McGrew. Treatment of Chronic Fatigue Syndrome and Fibromyalgia with D-Ribose– An Open-label, Multicenter Study, The Open Pain Journal 5 : 32-37(2012).
8. JACOB E. TEITELBAUM, M.D. CLARENCE JOHNSON, M.S. and JOHN ST. CYR, M.D., Ph.D. The Use of D-Ribose in Chronic Fatigue Syndrome and Fibromyalgia: A Pilot Study. THE JOURNAL OF ALTERNATIVE AND COMPLEMENTARY MEDICINE Volume 12, Number 9, pp. 857–862 (2006).
9. David J. Perkowski, Susan Wagner, Joseph R. Schneider and J. A. St. Cyr. A targeted metabolic protocol with D-ribose for off-pump coronary artery bypass procedures: a retrospective analysis. Ther Adv Cardiovasc Dis published online DOI: 10.1177/1753944711412421, (2011).
10. Ragavendra R. Baliga, MD, MBA James B. Young, MD. Editorial
Energizing Diastole, Heart Failure Clin 4 ix–xiii (2008).
11. Dean MacCarter, PhD, Nampalli Vijay, MD, Melinda Washam, MS, Linda Shecterle, PhD, Helen, Sierminski, BA, J.A. St. Cyr, MD, PhD, Aurora Denver Cardiology Associates, P.C., Denver, CO. D-Ribose Aids Advanced Ischemic Heart Failure Patients, International Journal of Cardiology, (2008).
12. Y. Hellsten, E.A. Richter, B. Kiens and J. Bangsbo. AMP deamination and purine exchange in human skeletal muscle during and after intense exercise, J. Physiol. 520:902-920 (1999).(this information is current as of May 17, 2006)
13. Effect of D-Ribose on Insulin and Blood Glucose: A
Chronological Examination (2003).
14. FALK, Darin J., HEELAN, Kate A., THYFAULT, John P., et al. Effects of effervescent creatine, ribose, and glutamine supplementation on muscular strength, muscular endurance, and body composition. The Journal of Strength & Conditioning Research, 2003, vol. 17, no 4, p. 810-816.
15. BERARDI, John M. et ZIEGENFUSS, Tim N. Effects of ribose supplementation on repeated sprint performance in men. The Journal of Strength & Conditioning Research, 2003, vol. 17, no 1, p. 47-52.
16. BRAULT, Jeffrey J. et TERJUNG, Ronald L. Purine salvage to adenine nucleotides in different skeletal muscle fiber types. Journal of applied physiology, 2001, vol. 91, no 1, p. 231-238.
17. HELLSTEN-WESTING, Y. L. V. A., NORMAN, BARBARA, BALSOM, PAUL D., et al. Decreased resting levels of adenine nucleotides in human skeletal muscle after high-intensity training. Journal of Applied Physiology, 1993, vol. 74, no 5, p. 2523-2528;
18. GROSS, M., KORMANN, B., et ZÖLLNER, N. Ribose administration during exercise: effects on substrates and products of energy metabolism in healthy subjects and a patient with myoadenylate deaminase deficiency. Klinische Wochenschrift, 1991, vol. 69, p. 151-155.
19. WAGNER, D. R., GRESSER, U., et ZÖLLNER, N. Effects of oral ribose on muscle metabolism during bicycle ergometer in AMPD-deficient patients. Annals of nutrition and metabolism, 1991, vol. 35, no 5, p. 297-302.
20. GROSS, M., REITER, S., et ZÖLLNER, N. Metabolism of D-ribose administered continuously to healthy persons and to patients with myoadenylate deaminase deficiency. Klinische Wochenschrift, 1989, vol. 67, p. 1205-1213.
21. Bioenergy Life Science, Inc. Brochure en ligne, Increased NAD,ATP and GSH., 2020, https://bioenergylifescience.fr/riagev/
22. Bioenergy Life Science, Inc. Brochure en ligne, Announcing the Next Generation in Skin Health Technology, 2021, https://bioenergylifescience.fr/riagev/
23. American Preclinical Services, Minneapolis, MN; Alex Xue, PhD, Bioenergy Life Science, Inc., Minneapolis, MN. Pharmacodynamics Study Summary of RiaGev™, https://bioenergylifescience.fr/riagev/
24. Bioenergy Life Science, Inc. (consulté le 11.07.2024) https://bioenergylifescience.fr/riagev/

Céramosides™

25. CHEN, Chun-yu, ZHANG, Jia-Qi, LI, Li, et al. Advanced glycation end products in the skin: Molecular mechanisms, methods of measurement, and inhibitory pathways. Frontiers in Medicine, 2022, vol. 9, p. 837222.
26. Seppic. Brochure d’étude en ligne. CERAMOSIDES™ Youthful and hydrated skin from within. 2023, https://www.seppic.com/fr
27. Seppic. Brochure d’étude en ligne. CERAMOSIDES™ Hair growth and strength from the inside out. 2023, https://www.seppic.com/fr
28. BIZOT, Valérie, CESTONE, Enza, MICHELOTTI, Angela, et al. Improving skin hydration and age-related symptoms by oral administration of wheat glucosylceramides and digalactosyl diglycerides: a human clinical study. Cosmetics, 2017, vol. 4, no 4, p. 37.
29. KERN, Catherine, DUDONNÉ, Stéphanie, et GARCIA, Christine. Dietary supplementation with a wheat polar lipid complex improves skin conditions in women with dry skin and mild‐to‐moderate skin aging. Journal of Cosmetic Dermatology, 2024, vol. 23, no 4, p. 1320-1330.
30. DUDONNÉ, Stéphanie, KERN, Catherine, et GARCIA, Christine. Efficacy of a wheat polar lipid complex in reducing hair loss and improving hair growth in healthy women: A randomized, double‐blind, placebo‐controlled clinical study. International Journal of Cosmetic Science, 2024, vol. 46, no 2, p. 284-296.
31. MASTROCOLA, Raffaella, DAL BELLO, Federica, CENTO, Alessia S., et al. Altered hepatic sphingolipid metabolism in insulin resistant mice: Role of advanced glycation endproducts. Free Radical Biology and Medicine, 2021, vol. 169, p. 425-435.
32. MECKFESSEL, Matthew H. et BRANDT, Staci. The structure, function, and importance of ceramides in skin and their use as therapeutic agents in skin-care products. Journal of the American Academy of Dermatology, 2014, vol. 71, no 1, p. 177-184.
33. SCHACHNER, Lawrence A., ALEXIS, Andrew F., ANDRIESSEN, Anneke, et al. Insights into acne and the skin barrier: Optimizing treatment regimens with ceramide‐containing skincare. Journal of Cosmetic Dermatology, 2023, vol. 22, no 11, p. 2902-2909.
34. DRAELOS, Zoe Diana. The effect of ceramide-containing skin care products on eczema resolution duration. Cutis, 2008, vol. 81, no 1, p. 87-91.

Resvératrol

35. ZHOU, Dan-Dan, LUO, Min, HUANG, Si-Yu, et al. Effects and mechanisms of resveratrol on aging and age‐related diseases. Oxidative medicine and cellular longevity, 2021, vol. 2021, no 1, p. 9932218.
36. Evolva. Brochure en ligne, Heart Health, 2022, https://veriteresveratrol.com/
37. Evolva. Brochure en ligne, Blood Glucose, 2022, https://veriteresveratrol.com/
38. Evolva. Brochure en ligne, Eye Health, 2022, https://veriteresveratrol.com/
39. Evolva. Brochure en ligne, Bone Health, 2022, https://veriteresveratrol.com/
40. Evolva. Brochure en ligne, resveratrol re-imagined™, 2021, https://veriteresveratrol.com/
41. Evolva. Brochure en ligne, Skin Health, 2022, https://veriteresveratrol.com/
42. POLJŠAK, Borut et DAHMANE, Raja. Free radicals and extrinsic skin aging. Dermatology research and practice, 2012, vol. 2012, no 1, p. 135206.
43. PATRICIA FARRIS, M., JEAN KRUTMANN, M., YUAN-HONG LI, M., et al. Resveratrol: A unique antioxidant offering a multi-mechanistic approach for treating aging skin. J Drugs Dermatol, 2013, vol. 12, no 12, p. 1389-1394.
44. BUONOCORE, Daniela, LAZZERETTI, Angelo, TOCABENS, Pedro, et al. Resveratrol-procyanidin blend: nutraceutical and antiaging efficacy evaluated in a placebocontrolled, double-blind study. Clinical, Cosmetic and Investigational Dermatology, 2012, p. 159-165.
45. BRITTON, Robert G., KOVOOR, Christina, et BROWN, Karen. Direct molecular targets of resveratrol: identifying key interactions to unlock complex mechanisms. Annals of the New York Academy of Sciences, 2015, vol. 1348, no 1, p. 124-133.
46. BERNARD et BERTHON. Resveratrol: an original mechanism on tyrosinase inhibition. International journal of cosmetic science, 2000, vol. 22, no 3, p. 219-226.
47. LEE, Taek Hwan, SEO, Jae Ok, BAEK, So-Hyeon, et al. Inhibitory effects of resveratrol on melanin synthesis in ultraviolet B-induced pigmentation in Guinea pig skin. Biomolecules & therapeutics, 2014, vol. 22, no 1, p. 35.
48. COENYE, Tom, BRACKMAN, Gilles, RIGOLE, Petra, et al. Eradication of Propionibacterium acnes biofilms by plant extracts and putative identification of icariin, resveratrol and salidroside as active compounds. Phytomedicine, 2012, vol. 19, no 5, p. 409-412.
49. KIM, So Young, HYUN, Moo Yeol, GO, Kyung Chan, et al. Resveratrol exerts growth inhibitory effects on human SZ95 sebocytes through the inactivation of the PI3-K/Akt pathway. International Journal of Molecular Medicine, 2015, vol. 35, no 4, p. 1042-1050.
50. FABBROCINI, Gabriella, STAIBANO, Stefania, DE ROSA, Giuseppe, et al. Resveratrol-containing gel for the treatment of acne vulgaris: a single-blind, vehicle-controlled, pilot study. American journal of clinical dermatology, 2011, vol. 12, p. 133-141.
51. POULSEN, Morten Møller, FJELDBORG, Karen, ORNSTRUP, Marie Juul, et al. Resveratrol and inflammation: Challenges in translating pre-clinical findings to improved patient outcomes. Biochimica et Biophysica Acta (BBA)-Molecular Basis of Disease, 2015, vol. 1852, no 6, p. 1124-1136.
52. KJÆR, Thomas Nordstrøm, THORSEN, Kasper, JESSEN, Niels, et al. Resveratrol ameliorates imiquimod-induced psoriasis-like skin inflammation in mice. PloS one, 2015, vol. 10, no 5, p. e0126599.
53. DEARY, Ian J., CORLEY, Janie, GOW, Alan J., et al. Age-associated cognitive decline. British medical bulletin, 2009, vol. 92, no 1, p. 135-152.
54. KIRK-SANCHEZ, Neva J. et MCGOUGH, Ellen L. Physical exercise and cognitive performance in the elderly: current perspectives. Clinical interventions in aging, 2014, p. 51-62.
55. WILLIAMS, Kristine N. et KEMPER, Susan. Interventions to reduce cognitive decline in aging. Journal of psychosocial nursing and mental health services, 2010, vol. 48, no 5, p. 42-51.
56. 00. EVANS, Hamish Michael, HOWE, Peter Ranald Charles, et WONG, Rachel Heloise Xiwen. Clinical evaluation of effects of chronic resveratrol supplementation on cerebrovascular function, cognition, mood, physical function and general well-being in postmenopausal women—rationale and study design. Nutrients, 2016, vol. 8, no 3, p. 150.
57. EVANS, Hamish M., HOWE, Peter RC, et WONG, Rachel HX. Effects of resveratrol on cognitive performance, mood and cerebrovascular function in post-menopausal women; a 14-week randomised placebo-controlled intervention trial. Nutrients, 2017, vol. 9, no 1, p. 27.
58. WIGHTMAN, Emma L., HASKELL-RAMSAY, Crystal F., REAY, Jonathon L., et al. The effects of chronic trans-resveratrol supplementation on aspects of cognitive function, mood, sleep, health and cerebral blood flow in healthy, young humans. British Journal of Nutrition, 2015, vol. 114, no 9, p. 1427-1437.
59. DEL FATTORE, Andrea, TETI, Anna, et RUCCI, Nadia. Bone cells and the mechanisms of bone remodelling. Frontiers in Bioscience-Elite, 2012, vol. 4, no 6, p. 2302-2321.
60. 3) Ginaldi L, Di Benedetto MC and De Martinis M. Osteoporosis, inflammation and ageing. Immunity & Ageing 2005;2:14.

Phytocelltec™ MD NU

61. Mibelle AG Biochemistry. Brochure en ligne, PhytoCellTec™ Md Nu Apple cell culture extract
for skin vitality, https://www.mibellebiochemistry.com/
62. BAUMANN, Julia, WANDREY, Franziska, NOWAK, Kathrin, et al. Nutritional supplementation of an apple callus extract to target epidermal aging. Journal of Food, Nutrition and Diet Science, 2024, p. 18-28.
63. Mibelle AG Biochemistry. Brochure en ligne, miRNA Quantification in Cultured Apple Fruit Cells and Fresh Apple Fruit Tissue, https://www.mibellebiochemistry.com/
64. SCHMID, D., SCHÜRCH, C., BLUM, P., et al. Plant Stem Cell Extract for Longevity of Skin and Hair. SOFW Journal-Seifen Ole Fette Wachse, 2011, vol. 137, no 5, p. 30.
65. SCHIRMER, Cedric, EIBL, Regine, MASCHKE, Rüdiger W., et al. Single‐use Technology for the Production of Cellular Agricultural Products: Where are We Today?. Chemie Ingenieur Technik, 2022, vol. 94, no 12, p. 2018-2025.
66. GOLDFADEN, GARY. ApplE StEm CEllS Offer Hope For.
67. PRHAL, Jelena, MILIĆ, Jela, KRAJIŠNIK, Danina, et al. Properties and use of plant stem cells in cosmetic products. Arhiv za farmaciju, 2014, vol. 64, no 1, p. 26-37.

Nutroxsun™

68. Nutroxun™ , Extrait de pomelo et romarin Bénéfices santé, consulté le 11.07.2024, https://www.elementa-ingredients.com/fr/ingredient/nutroxsun-solution-naturelle-protection-solaire
69. NOBILE, Vincenzo, MICHELOTTI, Angela, CESTONE, Enza, et al. Skin photoprotective and antiageing effects of a combination of rosemary (Rosmarinus officinalis) and grapefruit (Citrus paradisi) polyphenols. Food & nutrition research, 2016, vol. 60, no 1, p. 31871.
70. LI POMI, Federica, PAPA, Vincenzo, BORGIA, Francesco, et al. Rosmarinus officinalis and skin: antioxidant activity and possible therapeutical role in cutaneous diseases. Antioxidants, 2023, vol. 12, no 3, p. 680.
71. INCE, Bilsev, YILDIRIM, Alpagan Mustafa, OKUR, Mehmet Ihsan, et al. Effects of Rosmarinus officinalis on the survivability of random-patterned skin flaps: an experimental study. Journal of plastic surgery and hand surgery, 2015, vol. 49, no 2, p. 83-87.
72. TAKAYAMA, Katia S., MONTEIRO, Mariana C., SAITO, Priscila, et al. Rosmarinus officinalis extract-loaded emulgel prevents UVB irradiation damage to the skin. Anais da Academia Brasileira de Ciências, 2022, vol. 94, no 4, p. e20201058.
73. İNCE, Bilsev, BILGEN, Fatma, GÜNDEŞLIOĞLU, Ayşe Özlem, et al. Use of systemic rosmarinus officinalis to enhance the survival of random-pattern skin flaps. Balkan medical journal, 2016, vol. 33, no 6, p. 645-651.
74. MAO, Feng, WU, Zhongxiao, SHEN, Yanna, et al. Regulatory mechanism of rosemary extract (Rosmarinus officinalis) on human skin fibroblasts during ultraviolet A photoaging. Iranian Journal of Science and Technology, Transactions A: Science, 2021, vol. 45, p. 427-436.
75. NIETO, Gema, ROS, Gaspar, et CASTILLO, Julián. Antioxidant and antimicrobial properties of rosemary (Rosmarinus officinalis, L.): A review. Medicines, 2018, vol. 5, no 3, p. 98.
76. CHEUNG, Susan et TAI, Joseph. Anti-proliferative and antioxidant properties of rosemary Rosmarinus officinalis. Oncology reports, 2007, vol. 17, no 6, p. 1525-1531.
77. ETTER, Selma C. Rosmarinus officinalis as an antioxidant. Journal of herbs, spices & medicinal plants, 2005, vol. 11, no 1-2, p. 121-159.
78. HUSSAIN, Abdullah Ijaz, ANWAR, Farooq, CHATHA, Shahzad Ali Shahid, et al. Rosmarinus officinalis essential oil: antiproliferative, antioxidant and antibacterial activities. Brazilian Journal of Microbiology, 2010, vol. 41, p. 1070-1078.
79. GARBARINO, Juan Antonio, TRONCOSO, Nicolás, DELPIANO, Pia, et al. Antioxidant activity analysis for the selection of Rosmarinus officinalis L. Natural Product Communications, 2006, vol. 1, no 12, p. 1934578X0600101210.
80. LI POMI, Federica, PAPA, Vincenzo, BORGIA, Francesco, et al. Rosmarinus officinalis and skin: antioxidant activity and possible therapeutical role in cutaneous diseases. Antioxidants, 2023, vol. 12, no 3, p. 680.
81. JORDÁN, Maria J., LAX, Vanesa, ROTA, Maria C., et al. Effect of the phenological stage on the chemical composition, and antimicrobial and antioxidant properties of Rosmarinus officinalis L essential oil and its polyphenolic extract. Industrial crops and products, 2013, vol. 48, p. 144-152.
82. CHIANG, Hsiu‐Mei, LIN, Jen‐Wen, HSIAO, Pei‐Ling, et al. Hydrolysates of citrus plants stimulate melanogenesis protecting against UV‐induced dermal damage. Phytotherapy Research, 2011, vol. 25, no 4, p. 569-576.
83. ALRASHEID, Ayat Ahmed, MOHAMED, Alaa Abdulmoneim, MOHIELDIN, Einas Gamal, et al. Phytochemical investigation and assessment of antimicrobial, anti-inflammatory and antioxidant activities of Sudanese Citrus paradisi peel extract. Journal of Pharmacognosy and Phytotherapy, 2019, vol. 11, no 1, p. 1-8.
84. SICARI, V., PELLICANÒ, T. M., GIUFFRÈ, A. M., et al. Physical chemical properties and antioxidant capacities of grapefruit juice (Citrus paradisi) extracted from two different varieties. International Food Research Journal, 2018, vol. 25, no 5.
85. SEBGHATOLLAHI, Zahra, GHANADIAN, Mustafa, AGARWAL, Pooja, et al. Citrus flavonoids: Biological activities, implementation in skin health, and topical applications: A Review. ACS Food Science & Technology, 2022, vol. 2, no 9, p. 1417-1432.
86. LUKITANINGSIH, Endang, NUR, Syamsu, QONITHAH, Fadilah, et al. In vitro anti-wrinkle and tyrosinase inhibitory activities of grapefruit peel and strawberry extracts. Majalah Obat Tradisional, 2020, vol. 25, no 3, p. 182-189.
87. WEST, Brett J., DENG, Shixin, PALU, Afa Kehaati, et al. Vitamin C, grape seed extract and citrus bioflavonoids protect the skin against photoaging: a review. Journal of Biosciences and Medicines, 2020, vol. 8, no 12, p. 116.

Caviar® Biotec (PROTÉINE DE CAVIAR)

88. PARK, Jeongjin, KIM, Dakyung, LEE, Minhee, et al. Enzyme-treated caviar prevents UVB irradiation-induced skin photoaging. Marine Drugs, 2022, vol. 20, no 11, p. 685.
89. LEE, Kyung-Eun, NHO, Youn-Hwa, YUN, Seok Kyun, et al. Caviar extract and its constituent DHA inhibits UVB-irradiated skin aging by inducing adiponectin production. International journal of molecular sciences, 2020, vol. 21, no 9, p. 3383.
90. NA, Gwi Hwan, KIM, SukJin, JUNG, Hyun Mook, et al. Skin Anti-Aging Efficacy of Enzyme-Treated Supercritical Caviar Extract: A Randomized, Double-Blind, Placebo-Controlled Clinical Trial. Nutrients, 2023, vol. 16, no 1, p. 137.
91. MAROTTA, Francesco, POLIMENI, Ascanio, SOLIMENE, Umberto, et al. Beneficial modulation from a high-purity caviar-derived homogenate on chronological skin aging. Rejuvenation Research, 2012, vol. 15, no 2, p. 174-177.
92. ZDROJEWICZ, Zygmunt, WRÓBLEWSKA, Magdalena, TOMASZEWSKI, Łukasz, et al. Caviar–luxury or health?. Medycyna Rodzinna, 2016.
93. IMBERT, Isabelle, BOTTO, Jean‐Marie, FARRA, Claude D., et al. Modulation of telomere binding proteins: a future area of research for skin protection and anti‐aging target. Journal of Cosmetic Dermatology, 2012, vol. 11, no 2, p. 162-166.
94. YAGI, Masayuki et YONEI, Yoshikazu. Glycative stress and anti-aging: 7. Glycative stress and skin aging. Glycative Stress Res, 2018, vol. 5, no 1, p. 50-54.
95. MASAKI, Hitoshi. Role of antioxidants in the skin: anti-aging effects. Journal of dermatological science, 2010, vol. 58, no 2, p. 85-90.
96. YOO, Mi Ae, SONG, Young Keun, JANG, Hyein, et al. Profiling of skin anti-aging related proteins in human dermal fibroblasts by decursin in Angelica gigas Nakai. Korean Journal of Chemical Engineering, 2011, vol. 28, p. 880-885.
97. HAMEURY, Sebastien, BORDERIE, Laurent, MONNEUSE, Jean‐Marc, et al. Prediction of skin anti‐aging clinical benefits of an association of ingredients from marine and maritime origins: ex vivo evaluation using a label‐free quantitative proteomic and customized data processing approach. Journal of Cosmetic Dermatology, 2019, vol. 18, no 1, p. 355-370.

AUTRES INGREDIENTS

D-RIBOSE

98. FLANIGAN, Richard, MACCARTER, Dean, SHECTERLE, Linda M., et al. D-ribose aids fatigue in aging adults. The Journal Of Alternative And Complementary Medicine, 2010, vol. 16, no 5, p. 529.
99. ZHANG, Zhengang et FENG, W. A. N. G. Effects of aerobic exercise combined with D-ribose supplementation on anti-fatigue and anti-oxidation in mice. 2022.
100. SHECTERLE, Linda M. et ST. CYR, John A. Dermal benefits of topical D-ribose. Clinical, Cosmetic and Investigational Dermatology, 2009, p. 151-152.
101. WEI, Yan, HAN, Chan Shuai, ZHOU, Jun, et al. D-ribose in glycation and protein aggregation. Biochimica et Biophysica Acta (BBA)-General Subjects, 2012, vol. 1820, no 4, p. 488-494.
102. HAN, Chanshuai, LU, Yang, WEI, Yan, et al. D-ribose induces cellular protein glycation and impairs mouse spatial cognition. PLoS One, 2011, vol. 6, no 9, p. e24623.
103. XUE, Yongquan, SHAMP, Trisha, NAGANA GOWDA, G. A., et al. A combination of nicotinamide and D-ribose (RiaGev) is safe and effective to increase NAD+ metabolome in healthy middle-aged adults: a randomized, triple-blind, placebo-controlled, cross-over pilot clinical trial. Nutrients, 2022, vol. 14, no 11, p. 2219.
104. PAULY, Daniel F. et PEPINE, Carl J. D-Ribose as a supplement for cardiac energy metabolism. journal of Cardiovascular Pharmacology and Therapeutics, 2000, vol. 5, no 4, p. 249-258.
105. SEIFERT, John G., BRUMET, Allison, et ST CYR, John A. The influence of D-ribose ingestion and fitness level on performance and recovery. Journal of the International Society of Sports Nutrition, 2017, vol. 14, no 1, p. 47.
106. MAHONEY, Diane E., HIEBERT, John B., THIMMESCH, Amanda, et al. Understanding D-ribose and mitochondrial function. Advances in bioscience and clinical medicine, 2018, vol. 6, no 1, p. 1.
107. CAO, Wei, QIU, Junqiang, CAI, Tianwei, et al. Effect of D-ribose supplementation on delayed onset muscle soreness induced by plyometric exercise in college students. Journal of the International Society of Sports Nutrition, 2020, vol. 17, p. 1-9.
108. ADDIS, Paul, SHECTERLE, Linda M., et A. ST. CYR, John. Cellular protection during oxidative stress: a potential role for D-ribose and antioxidants. Journal of Dietary Supplements, 2012, vol. 9, no 3, p. 178-182.
109. TEITELBAUM, Jacob E., JOHNSON, Clarence, et CYR, John St. The use of D-ribose in chronic fatigue syndrome and fibromyalgia: a pilot study. Journal of Alternative & Complementary Medicine, 2006, vol. 12, no 9, p. 857-862.
110. SALTMAN, Adam E. D-ribose-l-cysteine supplementation enhances wound healing in a rodent model. The American Journal of Surgery, 2015, vol. 210, no 1, p. 153-158.

ASCORBIC ACID (VITAMINE C)

111. MEISTER, Alton. On the antioxidant effects of ascorbic acid and glutathione. Biochemical pharmacology, 1992, vol. 44, no 10, p. 1905-1915.
112. LEE, Kun Kook et CHOI, Jung‐Do. The effects of Areca catechu L extract on anti‐aging. International journal of cosmetic science, 1999, vol. 21, no 4, p. 285-295.
00. BONTÉ, Frédéric. Les produits de soin de la peau. l’actualité chimique, 2008, no 323-324, p. 52.
113. HADDADI, Hayat. Détermination de l’activité antioxydante de quelques fruits. 2005. Thèse de doctorat. Béjaia, Université Abderrahmane Mira. Faculté des Sciences de la nature et de la vie.
114. PULLAR, Juliet M., CARR, Anitra C., et VISSERS, Margreet. The roles of vitamin C in skin health. Nutrients, 2017, vol. 9, no 8, p. 866.
115. DARR, D., COMBS, S., DUNSTON, S., et al. Topical vitamin C protects porcine skin from ultraviolet radiation‐induced damage. British Journal of Dermatology, 1992, vol. 127, no 3, p. 247-253.
116. CARR, Anitra C. et MAGGINI, Silvia. Vitamin C and immune function. Nutrients, 2017, vol. 9, no 11, p. 1211.
117. CHAN, Alvin C. Partners in defense, vitamin E and vitamin C. Canadian journal of physiology and pharmacology, 1993, vol. 71, no 9, p. 725-731.
118. BUNDESEN, Herman N., ARON, Hans CS, GREENEBAUM, Regina S., et al. THE DETOXIFYING ACTION OF VITAMIN C (ASCORBIC ACID) IN ARSENICAL THERAPY: ASCORBIC ACID AS A PREVENTIVE OF REACTIONS OF HUMAN SKIN TO NEOARSPHENAMINE. Journal of the American Medical Association, 1941, vol. 117, no 20, p. 1692-1695.
119. BOYERA, N., GALEY, I., et BERNARD, B. A. Effect of vitamin C and its derivatives on collagen synthesis and cross‐linking by normal human fibroblasts. International journal of cosmetic science, 1998, vol. 20, no 3, p. 151-158.
120. CHEN, Juanjuan, LIU, Yang, ZHAO, Zhao, et al. Oxidative stress in the skin: Impact and related protection. International Journal of Cosmetic Science, 2021, vol. 43, no 5, p. 495-509.
121. WEST, Brett J., DENG, Shixin, PALU, Afa Kehaati, et al. Vitamin C, grape seed extract and citrus bioflavonoids protect the skin against photoaging: a review. Journal of Biosciences and Medicines, 2020, vol. 8, no 12, p. 116.
122. KOHL, E., STEINBAUER, J., LANDTHALER, M., et al. Skin ageing. Journal of the European academy of dermatology and venereology, 2011, vol. 25, no 8, p. 873-884.
123. ICHIHASHI, M., UEDA, M., BUDIYANTO, A., et al. UV-induced skin damage. Toxicology, 2003, vol. 189, no 1-2, p. 21-39.

NICOTINAMIDE (VITAMINE B3)

effects. Journal of cosmetic dermatology, 2014, vol. 13, no 4, p. 324-328.
125. SHALITA, Alan R., SMITH, J. Graham, PARISH, Lawrence Charles, et al. Topical nicotinamide compared with clindamycin gel in the treatment of inelammatory acne vulgaris. International journal of dermatology, 1995, vol. 34, no 6, p. 434-437.
126. DRAELOS, Zoe Diana, MATSUBARA, Akira, et SMILES, Kenneth. The effect of 2% niacinamide on facial sebum production. Journal of Cosmetic and Laser Therapy, 2006, vol. 8, no 2, p. 96-101.
127. BISSETT, Donald L., OBLONG, John E., et BERGE, Cynthia A. Niacinamide: AB vitamin that improves aging facial skin appearance. Dermatologic Surgery, 2005, vol. 31, p. 860-866.
128. CHEN, Andrew C. et DAMIAN, Diona L. Nicotinamide and the skin. Australasian Journal of Dermatology, 2014, vol. 55, no 3, p. 169-175.
00. BOO, Yong Chool. Mechanistic basis and clinical evidence for the applications of nicotinamide (niacinamide) to control skin aging and pigmentation. Antioxidants, 2021, vol. 10, no 8, p. 1315.
129. SOMA, Yoshinao, KASHIMA, Masato, IMAIZUMI, Akiko, et al. Moisturizing effects of topical nicotinamide on atopic dry skin. International journal of dermatology, 2005, vol. 44, no 3, p. 197-202.
130. GEHRING, W. Nicotinic acid/niacinamide and the skin. Journal of cosmetic dermatology, 2004, vol. 3, no 2, p. 88-93.
131. SNAIDR, Victoria A., DAMIAN, Diona L., et HALLIDAY, Gary M. Nicotinamide for photoprotection and skin cancer chemoprevention: A review of efficacy and safety. Experimental dermatology, 2019, vol. 28, p. 15-22.
132. OBLONG, John E. The evolving role of the NAD+/nicotinamide metabolome in skin homeostasis, cellular bioenergetics, and aging. DNA repair, 2014, vol. 23, p. 59-63.
134. BISSETT, Donald L., OBLONG, John E., et BERGE, Cynthia A. Niacinamide: AB vitamin that improves aging facial skin appearance. Dermatologic Surgery, 2005, vol. 31, p. 860-866.
135. BISSETT, D. L., MIYAMOTO, K., SUN, P., et al. Topical niacinamide reduces yellowing, wrinkling, red blotchiness, and hyperpigmented spots in aging facial skin 1. International journal of cosmetic science, 2004, vol. 26, no 5, p. 231-238.
136. BERSON, Diane S., OSBORNE, Rosemarie, OBLONG, John E., et al. Niacinamide. Cosmeceuticals and cosmetic practice, 2013, p. 103-112.

L-SELENOMETHIONINE

137. TAPIERO, H., TOWNSEND, D. M., et TEW, K. D. The antioxidant role of selenium and seleno-compounds. Biomedicine & pharmacotherapy, 2003, vol. 57, no 3-4, p. 134-144.
138. BURK, Raymond F. Selenium, an antioxidant nutrient. Nutrition in clinical Care, 2002, vol. 5, no 2, p. 75-79.
139. TINGGI, Ujang. Selenium: its role as antioxidant in human health. Environmental health and preventive medicine, 2008, vol. 13, p. 102-108.
140. KIEŁCZYKOWSKA, Małgorzata, KOCOT, Joanna, PAŹDZIOR, Marek, et al. Selenium-a fascinating antioxidant of protective properties. Adv Clin Exp Med, 2018, vol. 27, no 2, p. 245-255.
141. ZOIDIS, Evangelos, SEREMELIS, Isidoros, KONTOPOULOS, Nikolaos, et al. Selenium-dependent antioxidant enzymes: Actions and properties of selenoproteins. Antioxidants, 2018, vol. 7, no 5, p. 66.
142. BJØRKLUND, Geir, SHANAIDA, Mariia, LYSIUK, Roman, et al. Selenium: an antioxidant with a critical role in anti-aging. Molecules, 2022, vol. 27, no 19, p. 6613.
143. CAI, Zhonglin, ZHANG, Jianzhong, et LI, Hongjun. Selenium, aging and aging-related diseases. Aging clinical and experimental research, 2019, vol. 31, p. 1035-1047.
144. COSÍN-TOMÀS, Marta, SENSERRICH, Júlia, ARUMÍ-PLANAS, Marta, et al. Role of resveratrol and selenium on oxidative stress and expression of antioxidant and anti-aging genes in immortalized lymphocytes from Alzheimer’s disease patients. Nutrients, 2019, vol. 11, no 8, p. 1764.
145. KOYAMA, Hiroshi, ABDULAH, Rizky, et YAMAZAKI, Chihiro. The role of selenium for cancer chemoprevention and anti-aging. Biomed Res Trace Elements, 2009, vol. 20, no 1, p. 19-29.
146. ALEHAGEN, Urban, OPSTAD, Trine B., ALEXANDER, Jan, et al. Impact of selenium on biomarkers and clinical aspects related to ageing. A review. Biomolecules, 2021, vol. 11, no 10, p. 1478.
147. LI, Bo, LIU, Xu, YU, Tao, et al. Environmental selenium and human longevity: An ecogeochemical perspective. Chemosphere, 2024, vol. 347, p. 140691.
148. JOBEILI, Lara, ROUSSELLE, Patricia, BÉAL, David, et al. Selenium preserves keratinocyte stemness and delays senescence by maintaining epidermal adhesion. Aging (Albany NY), 2017, vol. 9, no 11, p. 2302.
149. MUJAHIDAH, Fatimah Fitriani, SUSILOWATI, Erna, MARHAMAH, Marhamah, et al. The Influence of Selenium on Telomere Length and DNA Damage as Indicators of Age-Related Changes: A Systematic Literature Review. Poltekita: Jurnal Ilmu Kesehatan, 2023, vol. 17, no 2, p. 318-325.
150. SHETH, Avani H., SEN, Dhrubo Jyoti, et DOSHI, Naman B. Effective Anti-Aging Tips You Would Be Glad To Know. Research Journal of Science and Technology, 2011, vol. 3, no 1, p. 1-11.
151. HARIHARAN, Sneha et DHARMARAJ, Selvakumar. Selenium and selenoproteins: It’s role in regulation of inflammation. Inflammopharmacology, 2020, vol. 28, p. 667-695.

ZINC BISGLYCINATE

152. OGAWA, Youichi, KAWAMURA, Tatsuyoshi, et SHIMADA, Shinji. Zinc and skin biology. Archives of biochemistry and biophysics, 2016, vol. 611, p. 113-119.
153. GLUTSCH, Valerie, HAMM, Henning, et GOEBELER, Matthias. Zinc and skin: an update. JDDG: Journal der Deutschen Dermatologischen Gesellschaft, 2019, vol. 17, no 6, p. 589-596.
154. ROSTAN, Elizabeth F., DEBUYS, Holly V., MADEY, Doren L., et al. Evidence supporting zinc as an important antioxidant for skin. International journal of dermatology, 2002, vol. 41, no 9, p. 606-611.
155. BAO, Bin, AHMAD, Aamir, AZMI, Asfar, et al. The biological significance of zinc in inflammation and aging. In : Inflammation, advancing age and nutrition. Academic Press, 2014. p. 15-27.
156. CABOT, Catalina, SIBOLE, John V., BARCELÓ, Juan, et al. Luxury zinc supply acts as antiaging agent and enhances reproductive fitness in Arabidopsis thaliana. Plant Science, 2021, vol. 304, p. 110805.
157. HAN, Bo, FANG, William H., ZHAO, Shuqing, et al. Zinc sulfide nanoparticles improve skin regeneration. Nanomedicine: Nanotechnology, Biology and Medicine, 2020, vol. 29, p. 102263.
158. FIVENSON, David P. The mechanisms of action of nicotinamide and zinc in inflammatory skin disease. Cutis, 2006, vol. 77, no 1 Suppl, p. 5-10.
160. WILSON, Dallas, VARIGOS, George, et ACKLAND, M. Leigh. Apoptosis may underlie the pathology of zinc‐deficient skin. Immunology and cell biology, 2006, vol. 84, no 1, p. 28-37.
161. MARET, Wolfgang et SANDSTEAD, Harold H. Zinc requirements and the risks and benefits of zinc supplementation. Journal of trace elements in medicine and biology, 2006, vol. 20, no 1, p. 3-18.
162. PRASAD, Ananda S., BECK, Frances WJ, BAO, Bin, et al. Zinc supplementation decreases incidence of infections in the elderly: effect of zinc on generation of cytokines and oxidative stress. The American journal of clinical nutrition, 2007, vol. 85, no 3, p. 837-844.
163. DUCHATEAU, Jean, DELEPESSE, Guy, VRIJENS, Roger, et al. Beneficial effects of oral zinc supplementation on the immune response of old people. The American journal of medicine, 1981, vol. 70, no 5, p. 1001-1004.
164. LAI, Jun, MOXEY, Annette, NOWAK, Gabriel, et al. The efficacy of zinc supplementation in depression: systematic review of randomised controlled trials. Journal of affective disorders, 2012, vol. 136, no 1-2, p. e31-e39.

GLYCINE

165. RAZAK, Meerza Abdul, BEGUM, Pathan Shajahan, VISWANATH, Buddolla, et al. Multifarious beneficial effect of nonessential amino acid, glycine: a review. Oxidative medicine and cellular longevity, 2017, vol. 2017, no 1, p. 1716701.
166. SEKHAR, Rajagopal V., PATEL, Sanjeet G., GUTHIKONDA, Anuradha P., et al. Deficient synthesis of glutathione underlies oxidative stress in aging and can be corrected by dietary cysteine and glycine supplementation. The American journal of clinical nutrition, 2011, vol. 94, no 3, p. 847-853.
167. DÍAZ-FLORES, Margarita, CRUZ, Miguel, DURAN-REYES, Genoveva, et al. Oral supplementation with glycine reduces oxidative stress in patients with metabolic syndrome, improving their systolic blood pressure. Canadian journal of physiology and pharmacology, 2013, vol. 91, no 10, p. 855-860.
168. AKINDE, D. O. Amino acid efficiency with dietary glycine supplementation: Part 1. World’s Poultry Science Journal, 2014, vol. 70, no 3, p. 461-474.
169. SEKHAR, Rajagopal V., MCKAY, Siripoom V., PATEL, Sanjeet G., et al. Glutathione synthesis is diminished in patients with uncontrolled diabetes and restored by dietary supplementation with cysteine and glycine. Diabetes care, 2011, vol. 34, no 1, p. 162-167.
170. NGUYEN, Dan, HSU JEAN, W., JAHOOR, Farook, et al. Effect of increasing glutathione with cysteine and glycine supplementation on mitochondrial fuel oxidation, insulin sensitivity, and body composition in older HIV-infected patients. The Journal of Clinical Endocrinology & Metabolism, 2014, vol. 99, no 1, p. 169-177.
171. BUCHMAN, A. L., O’BRIEN, W., OU, C. N., et al. The effect of arginine or glycine supplementation on gastrointestinal function, muscle injury, serum amino acid concentrations and performance during a marathon run. International journal of sports medicine, 1999, vol. 20, no 05, p. 315-321.
172. CHYUN, Jong-Hee et GRIMINGER, Paul. Improvement of nitrogen retention by arginine and glycine supplementation and its relation to collagen synthesis in traumatized mature and aged rats. The Journal of nutrition, 1984, vol. 114, no 9, p. 1697-1704.
173. XIE, Shiwei, ZHOU, Weiwen, TIAN, Lixia, et al. Effect of N-acetyl cysteine and glycine supplementation on growth performance, glutathione synthesis, anti-oxidative and immune ability of Nile tilapia, Oreochromis niloticus. Fish & shellfish immunology, 2016, vol. 55, p. 233-241.
174. HALL, John C. Glycine. Journal of Parenteral and Enteral Nutrition, 1998, vol. 22, no 6, p. 393-398.
175. KUMAR, Premranjan, LIU, Chun, HSU, Jean W., et al. Glycine and N‐acetylcysteine (GlyNAC) supplementation in older adults improves glutathione deficiency, oxidative stress, mitochondrial dysfunction, inflammation, insulin resistance, endothelial dysfunction, genotoxicity, muscle strength, and cognition: results of a pilot clinical trial. Clinical and translational medicine, 2021, vol. 11, no 3, p. e372.
176. LI, Peng et WU, Guoyao. Roles of dietary glycine, proline, and hydroxyproline in collagen synthesis and animal growth. Amino acids, 2018, vol. 50, p. 29-38.
177. DE PAZ-LUGO, Patricia, LUPIÁÑEZ, José Antonio, et MELÉNDEZ-HEVIA, Enrique. High glycine concentration increases collagen synthesis by articular chondrocytes in vitro: acute glycine deficiency could be an important cause of osteoarthritis. Amino acids, 2018, vol. 50, no 10, p. 1357-1365.
178. MELÉNDEZ-HEVIA, Enrique, DE PAZ-LUGO, Patricia, CORNISH-BOWDEN, Athel, et al. A weak link in metabolism: the metabolic capacity for glycine biosynthesis does not satisfy the need for collagen synthesis. Journal of biosciences, 2009, vol. 34, p. 853-872.
179. SÁ, Odara Maria de Sousa, LOPES, Nilza Nelly Fontana, ALVES, Maria Teresa Seixas, et al. Effects of glycine on collagen, PDGF, and EGF expression in model of oral mucositis. Nutrients, 2018, vol. 10, no 10, p. 1485.
180. PONNUSHA, Babu Shankar, SUBRAMANIYAM, Sathiyamoorthy, PASUPATHI, Palanisamy, et al. Antioxidant and Antimicrobial properties of Glycine Max-A review. Int J Cur Bio Med Sci., 2011, vol. 1, no 2, p. 49-62.
181. JOHNSON, Adiv A. et CUELLAR, Trinna L. Glycine and aging: Evidence and mechanisms. Ageing research reviews, 2023, vol. 87, p. 101922.
182. JAMES, S. et MORGANTI, P. Oral administration of Gelatin-glycine for aged skin. JOURNAL OF APPLIED COSMETOLOGY, 1994, vol. 12, p. 17-17.
183. BOJARSKA, Joanna. Amino acids and short peptides as anti-aging “Superfood”. Int. J. Nutr. Sci, 2020, vol. 5, no 1, p. 1039.

L-CARNOSINE

184. HIPKISS*, A. R. et BROWNSON, C. A possible new role for the anti-ageing peptide carnosine. Cellular and Molecular Life Sciences CMLS, 2000, vol. 57, p. 747-753.
185. HIPKISS, Alan R. Carnosine, a protective, anti-ageing peptide?. The international journal of biochemistry & cell biology, 1998, vol. 30, no 8, p. 863-868.
186. KIM, Yerin et KIM, Yuri. L-histidine and L-carnosine exert anti-brain aging effects in D-galactose-induced aged neuronal cells. Nutrition Research and Practice, 2020, vol. 14, no 3, p. 188-202.
187. BABIZHAYEV, M. A. Treatment of skin aging and photoaging with innovative oral dosage forms of nonhydrolized carnosine and carcinine. Int J Clin Derm Res, 2017, vol. 5, no 5, p. 116-143.
188. WANG, A. M., MA, C., XIE, Z. H., et al. Use of carnosine as a natural anti-senescence drug for human beings. BIOCHEMISTRY C/C OF BIOKHIMIIA, 2000, vol. 65, no 7, p. 869-871.
189. A BABIZHAYEV, Mark et E YEGOROV, Yegor. An “Enigmatic” l-Carnosine (β-Alanyl-l-Histidine)? Cell Proliferative Activity as a Fundamental Property of a Natural Dipeptide Inherent to Traditional Antioxidant, Anti-Aging Biological Activities: Balancing and a Hormonally Correct Agent, Novel patented oral therapy dosage formulation for mobility, skeletal muscle power and functional performance, hypothalamic-pituitary-brain relationship in health, aging and stress studies. Recent Patents on Drug Delivery & Formulation, 2015, vol. 9, no 1, p. 1-64.
190. HIPKISS, Alan R., BROWNSON, Carol, et CARRIER, Martin J. Carnosine, the anti-ageing, anti-oxidant dipeptide, may react with protein carbonyl groups. Mechanisms of ageing and development, 2001, vol. 122, no 13, p. 1431-1445.
191. HIPKISS, Alan R. Carnosine and its possible roles in nutrition and health. Advances in food and nutrition research, 2009, vol. 57, p. 87-154.
192. HIPKISS, Alan R. On the enigma of carnosine’s anti-ageing actions. Experimental gerontology, 2009, vol. 44, no 4, p. 237-242.
193. HIPKISS, Alan R. et BROWNSON, Carol. Carnosine reacts with protein carbonyl groups: another possible role for the anti-ageing peptide?. Biogerontology, 2000, vol. 1, p. 217-223.
194. WANG, Shiwei, NIU, Huanyun, LIU, Yao, et al. Clinical efficacy and safety of non-cross-linked hyaluronic acid combined with L-carnosine for horizontal neck wrinkles treatment. Aesthetic Plastic Surgery, 2021, vol. 45, no 6, p. 2912-2917.
195. REDDY, V. Prakash, GARRETT, Matthew R., PERRY, George, et al. Carnosine: a versatile antioxidant and antiglycating agent. Science of Aging Knowledge Environment, 2005, vol. 2005, no 18, p. pe12-pe12.
196. GUAITOLINI, Ennio, CAVEZZI, Attilio, COCCHI, Stefania, et al. Randomized, placebo-controlled study of a nutraceutical based on hyaluronic acid, L-carnosine, and methylsulfonylmethane in facial skin aesthetics and well-being. The Journal of clinical and aesthetic dermatology, 2019, vol. 12, no 4, p. 40.
197. SHAO, Lan, LI, Qing-huan, et TAN, Zheng. L-carnosine reduces telomere damage and shortening rate in cultured normal fibroblasts. Biochemical and biophysical research communications, 2004, vol. 324, no 2, p. 931-936.
198. ABDELKADER, Hamdy, LONGMAN, Michael, ALANY, Raid G., et al. On the anticataractogenic effects of L‐carnosine: Is it best described as an antioxidant, metal‐chelating agent or glycation inhibitor?. Oxidative Medicine and Cellular Longevity, 2016, vol. 2016, no 1, p. 3240261.
199. SURESHKUMAR, Kaoshik, DURAIRAJ, Mahesh, SRINIVASAN, Kaviya, et al. Effect of L-carnosine in patients with age-related diseases: a systematic review and meta-analysis. Frontiers in Bioscience-Landmark, 2023, vol. 28, no 1, p. 18.
200. TURNER, Mark D., SALE, Craig, GARNER, A. Christopher, et al. Anti-cancer actions of carnosine and the restoration of normal cellular homeostasis. Biochimica et Biophysica Acta (BBA)-Molecular Cell Research, 2021, vol. 1868, no 11, p. 119117.

PÉPINS DE RAISIN

201. MANDIC, Anamarija I., ĐILAS, Sonja M., ĆETKOVIĆ, Gordana S., et al. Polyphenolic composition and antioxidant activities of grape seed extract. International Journal of Food Properties, 2008, vol. 11, no 4, p. 713-726.
202. CHEDEA, Veronica Sanda, BRAICU, Cornelia, et SOCACIU, Carmen. Antioxidant/prooxidant activity of a polyphenolic grape seed extract. Food Chemistry, 2010, vol. 121, no 1, p. 132-139.
203. NUTTALL, S. L., KENDALL, M. J., BOMBARDELLI, E., et al. An evaluation of the antioxidant activity of a standardized grape seed extract, Leucoselect®. Journal of clinical pharmacy and therapeutics, 1998, vol. 23, no 5, p. 385-389.
204. BAYDAR, Nilgün Göktürk, ÖZKAN, Gülcan, et YAŞAR, Samim. Evaluation of the antiradical and antioxidant potential of grape extracts. Food control, 2007, vol. 18, no 9, p. 1131-1136.
205. TAO, Kan, GUO, Lili, HU, Xincheng, et al. Encapsulated activated grape seed extract: a novel formulation with anti-aging, skin-brightening, and hydration properties. Cosmetics, 2021, vol. 9, no 1, p. 4.
206. FOSHATI, Sahar, ROUHANI, Mohammad Hossein, et AMANI, Reza. The effect of grape seed extract supplementation on oxidative stress and inflammation: a systematic review and meta‐analysis of controlled trials. International Journal of Clinical Practice, 2021, vol. 75, no 11, p. e14469.
207. BELVIRANLI, Muaz, GÖKBEL, Hakkı, OKUDAN, Nilsel, et al. Effects of grape seed extract supplementation on exercise-induced oxidative stress in rats. British journal of nutrition, 2012, vol. 108, no 2, p. 249-256.
208. DELIMONT, Nicole M. et CARLSON, Brandi N. Prevention of dental caries by grape seed extract supplementation: a systematic review. Nutrition and health, 2020, vol. 26, no 1, p. 43-52.
209. TAGHIZADEH, Mohsen, MALEKIAN, Elaheh, MEMARZADEH, Mohammad Reza, et al. Grape seed extract supplementation and the effects on the biomarkers of oxidative stress and metabolic profiles in female volleyball players: a randomized, double-blind, placebo-controlled clinical trial. Iranian Red Crescent Medical Journal, 2016, vol. 18, no 9.
210. FOSHATI, Sahar, NOURIPOUR, Fatemeh, SADEGHI, Erfan, et al. The effect of grape (Vitis vinifera) seed extract supplementation on flow-mediated dilation, blood pressure, and heart rate: A systematic review and meta-analysis of controlled trials with duration-and dose-response analysis. Pharmacological Research, 2022, vol. 175, p. 105905.
211. KATIYAR, Santosh K. Grape seed proanthocyanidines and skin cancer prevention: inhibition of oxidative stress and protection of immune system. Molecular nutrition & food research, 2008, vol. 52, no S1, p. S71-S76.
212. MOHANSRINIVASAN, V., DEVI C, Subathra, DEORI, Meenakshi, et al. Exploring the anticancer activity of grape seed extract on skin cancer cell lines A431. Brazilian Archives of Biology and Technology, 2015, vol. 58, p. 540-546.
213. YILMAZ, Yusuf et TOLEDO, Romeo T. Health aspects of functional grape seed constituents. Trends in food science & technology, 2004, vol. 15, no 9, p. 422-433.
214. PERDE-SCHREPLER, Maria, CHERECHES, Gabriela, BRIE, Ioana, et al. Grape seed extract as photochemopreventive agent against UVB-induced skin cancer. Journal of Photochemistry and Photobiology B: Biology, 2013, vol. 118, p. 16-21.
215. YILMAZ, Yusuf et TOLEDO, Romeo T. Major flavonoids in grape seeds and skins: antioxidant capacity of catechin, epicatechin, and gallic acid. Journal of agricultural and food chemistry, 2004, vol. 52, no 2, p. 255-260.
216. BONINA, Francesco, LANZA, Maria, MONTENEGRO, Lucia, et al. Flavonoids as potential protective agents against photo-oxidative skin damage. International Journal of Pharmaceutics, 1996, vol. 145, no 1-2, p. 87-94.
217. DOMASZEWSKA-SZOSTEK, Anna, PUZIANOWSKA-KUŹNICKA, Monika, et KURYŁOWICZ, Alina. Flavonoids in skin senescence prevention and treatment. International Journal of Molecular Sciences, 2021, vol. 22, no 13, p. 6814.
218. MA, Emily Z. et KHACHEMOUNE, Amor. Flavonoids and their therapeutic applications in skin diseases. Archives of dermatological research, 2023, vol. 315, no 3, p. 321-331.
219. STAHL, Wilhelm et SIES, Helmut. Carotenoids and flavonoids contribute to nutritional protection against skin damage from sunlight. Molecular biotechnology, 2007, vol. 37, p. 26-30.
220. CIJO GEORGE, Vazhappilly, VIJAYAKUMARAN VIJESH, Vijayabhavanath, INOKA MADUMANI AMARARATHNA, Dehigaspege, et al. Mechanism of action of flavonoids in prevention of inflammation-associated skin cancer. Current Medicinal Chemistry, 2016, vol. 23, no 32, p. 3697-3716.
221. SOLOVCHENKO, Alexei et SCHMITZ‐EIBERGER, Michaela. Significance of skin flavonoids for UV‐B‐protection in apple fruits. Journal of experimental botany, 2003, vol. 54, no 389, p. 1977-1984.
222. LEE, Jaeeun, PARK, Seyeon, LEE, Jaeeun, et al. Effects of flavonoids on skin according to their structural characteristics: a review. Asian Journal of Beauty and Cosmetology, 2022, vol. 20, no 1, p. 133-143.
223. SEBGHATOLLAHI, Zahra, GHANADIAN, Mustafa, AGARWAL, Pooja, et al. Citrus flavonoids: Biological activities, implementation in skin health, and topical applications: A Review. ACS Food Science & Technology, 2022, vol. 2, no 9, p. 1417-1432.
224. GEORGIEV, Vasil, ANANGA, Anthony, et TSOLOVA, Violeta. Recent advances and uses of grape flavonoids as nutraceuticals. Nutrients, 2014, vol. 6, no 1, p. 391-415.
225. HUNTLEY, A. L. Grape flavonoids and menopausal health. Menopause International, 2007, vol. 13, no 4, p. 165-169.

JUS CONCENTRÉ DE RAISIN BIO

226. BARBALHO, Sandra Maria, BUENO OTTOBONI, Alda Maria M., FIORINI, Adriana Maria Ragassi, et al. Grape juice or wine: which is the best option?. Critical reviews in food science and nutrition, 2020, vol. 60, no 22, p. 3876-3889.
227. COSME, Fernanda, PINTO, Teresa, et VILELA, Alice. Phenolic compounds and antioxidant activity in grape juices: A chemical and sensory view. Beverages, 2018, vol. 4, no 1, p. 22.
228. 00. ROWE, Cheryl A., NANTZ, Meri P., NIEVES JR, Carmelo, et al. Regular consumption of concord grape juice benefits human immunity. Journal of medicinal food, 2011, vol. 14, no 1-2, p. 69-78.
229. KRIKORIAN, Robert, BOESPFLUG, Erin L., FLECK, David E., et al. Concord grape juice supplementation and neurocognitive function in human aging. Journal of agricultural and food chemistry, 2012, vol. 60, no 23, p. 5736-5742.
230. HOLLIS, James H., HOUCHINS, Jenny A., BLUMBERG, Jeffrey B., et al. Effects of concord grape juice on appetite, diet, body weight, lipid profile, and antioxidant status of adults. Journal of the American College of Nutrition, 2009, vol. 28, no 5, p. 574-582.
231. FOLTS, John D. Potential health benefits from the flavonoids in grape products on vascular disease. Flavonoids in cell function, 2002, p. 95-111.
232. BLUMBERG, Jeffrey B., VITA, Joseph A., et CHEN, C.-Y. Oliver. Concord grape juice polyphenols and cardiovascular risk factors: Dose-response relationships. Nutrients, 2015, vol. 7, no 12, p. 10032-10052.
233. SARA JANITHA, R. Nutrition profile of grape juice–a review. History, 2015, vol. 22, no 76, p. 34-46.
234. SABRA, Ali, NETTICADAN, Thomas, et WIJEKOON, Champa. Grape bioactive molecules, and the potential health benefits in reducing the risk of heart diseases. Food Chemistry: X, 2021, vol. 12, p. 100149.
235. YUAN, Linhong, MENG, Liping, MA, Weiwei, et al. Impact of apple and grape juice consumption on the antioxidant status in healthy subjects. International journal of food sciences and nutrition, 2011, vol. 62, no 8, p. 844-850.
236. AHMADI, Latifeh, EL-KUBBE, Alia, et RONEY, Sarah K. Potential cardio-protective effects of green grape juice: a review. Current Nutrition & Food Science, 2019, vol. 15, no 3, p. 202-207.
237. BURIN, Vívian Maria, FALCÃO, Leila Denise, GONZAGA, Luciano Valdemiro, et al. Colour, phenolic content and antioxidant activity of grape juice. Food science and technology, 2010, vol. 30, p. 1027-1032.
238. BATU, Ali et KIRMACI, Bilal. Red grape juice and human health. Electronic Journal of Food Technologies, 2007, vol. 3, p. 35-45..

MIEL TOUTES FLEURS

239. JUSZCZAK, Lesław, FLORKIEWICZ, Adam, SOCHA, Robert, et al. Effect of honey supplementation with bee products on quality parameters and mineral composition. Emirates Journal of Food and Agriculture, 2018, vol. 30, no 12, p. 990-997.
240. HADI, Hazrina, SYED OMAR, Syarifah Shakira, et AWADH, Ammar Ihsan. Honey, a gift from nature to health and beauty: A review. British Journal of Pharmacy, 2016, vol. 1, no 1, p. 46-54.
241. MANYI-LOH, Christy E., CLARKE, Anna M., et NDIP, Roland N. An overview of honey: Therapeutic properties and contribution in nutrition and human health. African Journal of Microbiology Research, 2011, vol. 5, no 8, p. 844-852.
242. SABA, Z. H., SUZANA, M., et MY, Yasmin Anum. Honey: Food or medicine. Med. Health, 2013, vol. 8, no 1, p. 3-18.
243. DAR, Shahnawaz Ahmad, FAROOK, Umer Bin, RASOOL, Kawsar, et al. Honey: classification, composition, safety, quality issues and health benefits. In : Advanced Techniques of Honey Analysis. Academic Press, 2024. p. 1-37.
244. SAMARGHANDIAN, Saeed, FARKHONDEH, Tahereh, et SAMINI, Fariborz. Honey and health: A review of recent clinical research. Pharmacognosy research, 2017, vol. 9, no 2, p. 121.
245. CORTÉS, Manuel E., VIGIL, Pilar, et MONTENEGRO, Gloria. The medicinal value of honey: a review on its benefits to human health, with a special focus on its effects on glycemic regulation. Ciencia e investigación agraria: revista latinoamericana de ciencias de la agricultura, 2011, vol. 38, no 2, p. 303-317.

EXTRAIT D’HIBISCUS

246. DI MARTINO, O., TITO, A., DE LUCIA, A., et al. Hibiscus syriacus extract from an established cell culture stimulates skin wound healing. BioMed Research International, 2017, vol. 2017, no 1, p. 7932019.
247. SHARMA, Sonia et SULTANA, Sarwat. Effect of Hibiscus rosa sinensis extract on hyperproliferation and oxidative damage caused by benzoyl peroxide and ultraviolet radiations in mouse skin. Basic & clinical pharmacology & toxicology, 2004, vol. 95, no 5, p. 220-225.
248. SIM, Yan Yi et NYAM, Kar Lin. Application of Hibiscus cannabinus L.(kenaf) leaves extract as skin whitening and anti-aging agents in natural cosmetic prototype. Industrial Crops and Products, 2021, vol. 167, p. 113491.
249. WANG, Duanyang, NAGATA, Maki, MATSUMOTO, Masako, et al. Potential of Hibiscus sabdariffa L. and hibiscus acid to reverse skin aging. Molecules, 2022, vol. 27, no 18, p. 6076.
250. HEMARANA, K., JEYASHREE, K. V., BABU, M. M., et al. Preliminary bioactive compounds screening and antibacterial activity of methanolic extract of Hibiscus rosasinensis against selected skin pathogens. 2014.
251. YANG, Jung-Eun, NGO, Hien TT, HWANG, Eunson, et al. Dietary enzyme-treated Hibiscus syriacus L. protects skin against chronic UVB-induced photoaging via enhancement of skin hydration and collagen synthesis. Archives of biochemistry and biophysics, 2019, vol. 662, p. 190-200.
252. YANG, Jung-Eun, PARK, Sul Woong, NGO, Hien T. T., et al. Skin-protective and anti-inflammatory effects of Hibiscus syriacus L.(Mugunghwa): A comparative study of five parts of the plant. Pharmacognosy Magazine, 2020, vol. 16, no 67.
253. PARK, Jung Min, CHOI, Jae Eun, LEE, Young Ki, et al. Antioxidant and anti-inflammatory responses of pycnogenol, hibiscus flower extract, and niacin in skin epithelial cells. disease management, 2023, vol. 13, p. 14.
254. SIDRAM, A. Nevade, LOKAPURE, Sachin G., et KALYANE, N. V. Study on anti-solar activity of ethanolic extract of flower of Hibiscus Rosa-sinensis Linn. Research Journal of Pharmacy and Technology, 2011, vol. 4, no 3, p. 472-473.

RACINE D’ASTRAGALE

255. JUNG, Taek-Kyu, KIM, Mi-Jin, LIM, Kyung-Ran, et al. Moisturizing and anti-oxidation effect of Astragalus membranaceus root extract. Journal of the society of cosmetic scientists of Korea, 2006, vol. 32, no 3, p. 193-200.
256. KIM, Mi Jin, LIM, Kyung Ran, JUNG, Taek Kyu, et al. Anti-aging effect of Astragalus membranaceus root extract. Journal of the Society of Cosmetic Scientists of Korea, 2007, vol. 33, no 33, p. 33-40.
257. HONG, Min Jung, KO, Eun Bit, PARK, Seong Kyu, et al. Inhibitory effect of Astragalus membranaceus root on matrix metalloproteinase-1 collagenase expression and procollagen destruction in ultraviolet B-irradiated human dermal fibroblasts by suppressing nuclear factor kappa-B activity. Journal of Pharmacy and Pharmacology, 2013, vol. 65, no 1, p. 142-148.
258. SHAHRAJABIAN, Mohamad Hesam, SUN, Wenli, et CHENG, Qi. Astragalus, an ancient medicinal root in traditional Chinese medicine, a gift from silk road. Int. J. Agric. Biol. Sci, 2019, vol. 3, p. 27-38.
259. LIU, Ping, ZHAO, Haiping, et LUO, Yumin. Anti-aging implications of Astragalus membranaceus (Huangqi): a well-known Chinese tonic. Aging and disease, 2017, vol. 8, no 6, p. 868.
260. LI, Xing-Tai, ZHANG, Ya-Kui, KUANG, Hai-Xue, et al. Mitochondrial protection and anti-aging activity of Astragalus polysaccharides and their potential mechanism. International Journal of Molecular Sciences, 2012, vol. 13, no 2, p. 1747-1761.
261. YAN, Xinlei, MIAO, Jing, ZHANG, Bao, et al. Study on semi-bionic extraction of Astragalus polysaccharide and its anti-aging activity in vivo. Frontiers in Nutrition, 2023, vol. 10, p. 1201919.
262. BEREZUTSKY, M. A., DURNOVA, N. A., et VLASOVA, I. A. Experimental and clinical studies of mechanisms of the antiaging effects of chemical compounds in Astragalus membranaceus. Advances in Gerontology, 2020, vol. 10, p. 142-149.
263. LEI, Hong, WANG, Bin, LI, Wei-Ping, et al. Anti-aging effect of astragalosides and its mechanism of action. Acta Pharmacologica Sinica, 2003, vol. 24, no 3, p. 230-234.
264. LEI, Hong, WANG, Bin, LI, Wei-Ping, et al. Anti-oxidative effect of total extract of astragalus (TEA) on aging mice. Chinese Journal of Clinical Pharmacology and Therapeutics, 2000, vol. 5, no 4, p. 298.
265. HU, Y. L., XU, C. L., WANG, Y. Z., et al. Effect of dried roots of Astragalus membranaceus in the diets of young growing pigs on growth performance and immune function. Journal of Animal and Feed Sciences, 2006, vol. 15, no 4, p. 599.
266. WANG, X. J., DING, L. M., WEI, H. Y., et al. Astragalus membranaceus root supplementation improves average daily gain, rumen fermentation, serum immunity and antioxidant indices of Tibetan sheep. Animal, 2021, vol. 15, no 1, p. 100061.
267. HAO, Xiaoyan, WANG, Pengju, REN, Youshe, et al. Effects of Astragalus membranaceus roots supplementation on growth performance, serum antioxidant and immune response in finishing lambs. Asian-Australasian journal of animal sciences, 2020, vol. 33, no 6, p. 965.
268. QADER, Mallique, XU, Jian, YANG, Yuejun, et al. Chemistry behind the immunomodulatory activity of Astragalus membranaceus. Chinese Medicine and Culture, 2021, vol. 4, no 4, p. 201-210.
269. KHAN, Humaira Majeed, RAZA, Syeda Maryam, ANJUM, Aftab Ahmad, et al. Antiviral, embryo toxic and cytotoxic activities of Astragalus membranaceus root extracts. Pakistan journal of pharmaceutical sciences, 2019, vol. 32, no 1, p. 137-143.
270. GHABESHI, Soad, MOUSAVIZADEH, Leila, et GHASEMI, Sorayya. Enhancing the Antiviral Potential and Anti-inflammatory Properties of Astragalus membranaceus: A Comprehensive Review. Anti-Inflammatory & Anti-Allergy Agents in Medicinal Chemistry (Formerly Current Medicinal Chemistry-Anti-Inflammatory and Anti-Allergy Agents), 2023, vol. 22, no 4, p. 211-219.
271. WEI, Haiyan, DING, Luming, WANG, Xianju, et al. Astragalus root extract improved average daily gain, immunity, antioxidant status and ruminal microbiota of early weaned yak

Les allégations présentées dans ce document sont basées sur des preuves scientifiques rigoureuses et conformes aux réglementations actuelles concernant les compléments alimentaires. Cette bibliographie vise à garantir la transparence et la conformité légale des informations fournies sur la Hectyl JVCE® FORMULA. Les informations contenues dans cette bibliographie ont été recueillies et présentées conformément aux exigences réglementaires en vigueur, notamment le règlement (CE) n° 1924/2006 relatif aux allégations nutritionnelles et de santé portant sur les denrées alimentaires. Les déclarations sur ce produit n’ont pas pour but de diagnostiquer, traiter, guérir ou prévenir une maladie. Il est important de rappeler que les compléments alimentaires ne doivent pas se substituer à une alimentation variée et équilibrée ni à un mode de vie sain. En cas de doute, veuillez consulter un professionnel de santé.

Mise à jour le 17.07.2024