Glycation: Understanding its effects on your skin and how to prevent it

Skin aging is influenced by many factors, and one of the often overlooked but formidable processes is glycation. This phenomenon directly contributes to the appearance of signs of aging, such as wrinkles, sagging skin, and loss of elasticity. At Hectyl, we are committed to helping you understand these mechanisms to better protect your skin and preserve its youthfulness. In this article, we will explore in detail what glycation is, its effects on the skin, and how to effectively prevent it.

What is glycation?

Glycation is a chemical reaction that occurs when sugars (glucose, fructose, etc.) bind to proteins in our bodies, including collagen and elastin, two essential components for skin firmness and suppleness. This reaction forms advanced glycation end-products (AGEs), which alter protein structure and function. By accumulating these AGEs, the skin loses its tone and shows visible signs of aging.

The effects of glycation on the skin

When collagen and elastin proteins are damaged by glycation, they become rigid and less functional. Here are the main visible effects of glycation on the skin:

  1. Loss of elasticity : Glycation weakens collagen and elastin fibers, making skin less firm and more likely to sag.
  2. Appearance of wrinkles : Glycated proteins become rigid, which leads to a loss of skin flexibility and the formation of wrinkles, particularly around the eyes and mouth.
  3. Dull complexion : AGEs interfere with cell regeneration, reducing the skin's natural radiance and promoting a duller, uneven complexion.
  4. Sagging Skin : Due to the breakdown of supporting fibers, the skin loses its ability to support itself, which can lead to noticeable sagging in the face, neck, and jawline.
  5. Inflammation and sensitization : AGEs promote chronic inflammation of the skin, which can worsen conditions such as eczema or rosacea.

Factors that accelerate glycation

There are several things that can speed up the glycation process in the body, including:

  1. Excessive sugar consumption : Sugar is the main driver of glycation. A diet high in simple sugars, such as pastries, sodas, and processed foods, significantly increases the production of AGEs.
  2. UV exposure : Ultraviolet rays, in addition to causing direct damage to the skin, promote the formation of free radicals that accelerate glycation.
  3. Smoking : Not only is smoking a major cause of premature aging, it also stimulates the formation of AGEs, thereby reducing the quality of collagen.
  4. Oxidative stress : Exposure to environmental pollutants and internal oxidative stress increase free radical levels, which, in addition to accelerating aging, stimulate glycation.
  5. Age : As we age, our bodies become less efficient at repairing cellular damage, and the effects of glycation become more visible.

How to prevent glycation?

Although glycation is a natural phenomenon, it is possible to slow it down and mitigate its effects with certain habits and appropriate care. Here are some tips to preserve the youthfulness of your skin:

  1. Adopt a low-glycemic diet : Limit your intake of fast-acting sugars and favor foods rich in antioxidants, such as fruits, vegetables, nuts, and oily fish. These help neutralize free radicals and reduce the formation of AGEs.
  2. Use antioxidant-rich products : Topical skincare products containing ingredients like vitamin C , vitamin E , retinol , or polyphenols help fight free radicals and protect skin from the damaging effects of glycation.
  3. Protect yourself from the sun : Daily application of a broad-spectrum sunscreen protects skin from UV damage, which exacerbates the glycation process. Use an SPF of 30 or higher for effective protection.
  4. Quit smoking : If you smoke, quitting is one of the best things you can do to prevent premature aging and reduce the production of AGEs.
  5. Hydrate your skin : Hydration helps maintain the skin barrier, which protects collagen and elastin fibers from external aggressions.
  6. Jouvence Supplements : JVCE_03 rich in L-carnosine will help you counter the effects of glycation by limiting the formation of AGEs and stimulating cell renewal.
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