HECTYL - Scientific & Regulatory References
COMPLETE BIBLIOGRAPHY
As part of the design and formulation of its premium nutri-cosmetic products, Hectyl is committed to ensuring the transparency and veracity of its claims. JVCE ® FORMULA products incorporate patented ingredients and components rigorously selected for their scientifically proven benefits on health and beauty.
To support these claims and ensure reliable and accurate information, Hectyl has compiled a collection of official scientific studies, available online. This bibliography includes research and publications that validate the efficacy and safety of the ingredients used in Hectyl formulas. Each reference was chosen for its academic seriousness and significant contribution to knowledge in the field of nutri-cosmetics.
The studies included in this bibliography address various aspects, including:
- the mechanisms of action of the ingredients;
- the results of clinical trials;
- the benefits for the skin and overall health.
With this documentation, Hectyl wishes to offer its customers and partners an in-depth understanding of the scientific basis on which the JVCE ® FORMULA is based and to strengthen their confidence in the excellence of its products.
PATENTED INGREDIENTS
RiaGev-WS™
1. Hellsten Y, Skadhauge L, Bangsbo J. Effect of Ribose Supplementation on Resynthesis of Adenine Nucleotides after Intermittent Training in Humans, Am J Physiol Regul Integr Comp Physiol; 286:R182-R188 (2004).
2. Berardi, JM, and TN Ziegenfuss. Effects of ribose supplementation on repeated sprint performance in men. J.Strength Cond. Res. 17(1):47–52. (2003).
3. Falk, DJ, KA Heelan, JP Thyfault, and AJ Koch. Effects of effervescent creatine, ribose, and glutamine supplementation on muscular strength, muscular endurance, and body composition. J.Strength Cond. Res. 17(4):810–816. (2003).
4. Darin Van Gammeren, MAEd, CSCS, Darin Falk, MAEd and Jose Antonia, PhD, The Effect of Four Weeks of Ribose Supplementation on Body Composition and Exercise Performance in Healthy, Young, Male Recreational Bodybuilders: A Double-Blind Placebo-Controlled Trial, Curr Ther Clin Exp. 63:486-195 (2002).
5. M. Gross, B. Kormann, and N. Zöllner. Klin Wochenschr 69:151-155 (1991).
6. Joanne S. Ingwall, PhD. On the Hypothesis that the Failing Heart Is Energy Starved: Lesson Learned from the Metabolism of ATP and Creatine, Current Hypertension Reports, 8:457-464 (2006).
7. Jacob Teitelbaum, Janelle Jandrain and Ryan McGrew. Treatment of Chronic Fatigue Syndrome and Fibromyalgia with D-Ribose–An Open-label, Multicenter Study, The Open Pain Journal 5: 32-37(2012).
8. JACOB E. TEITELBAUM, MD CLARENCE JOHNSON, MS and JOHN ST. CYR, MD, Ph.D. The Use of D-Ribose in Chronic Fatigue Syndrome and Fibromyalgia: A Pilot Study. THE JOURNAL OF ALTERNATIVE AND COMPLEMENTARY MEDICINE Volume 12, Number 9, pp. 857–862 (2006).
9. David J. Perkowski, Susan Wagner, Joseph R. Schneider and JA St. Cyr. A targeted metabolic protocol with D-ribose for off-pump coronary artery bypass procedures: a retrospective analysis. Ther Adv Cardiovasc Dis published online DOI: 10.1177/1753944711412421, (2011).
10. Ragavendra R. Baliga, MD, MBA James B. Young, MD. Editorial
Energizing Diastole, Heart Failure Clin 4 ix–xiii (2008).
11. Dean MacCarter, PhD, Nampalli Vijay, MD, Melinda Washam, MS, Linda Shecterle, PhD, Helen, Sierminski, BA, JA St. Cyr, MD, PhD, Aurora Denver Cardiology Associates, PC, Denver, CO. D-Ribose Aids Advanced Ischemic Heart Failure Patients, International Journal of Cardiology, (2008).
12. Y. Hellsten, EA Richter, B. Kiens and J. Bangsbo. AMP deamination and purine exchange in human skeletal muscle during and after intense exercise, J. Physiol. 520:902-920 (1999).(this information is current as of May 17, 2006)
13. Effect of D-Ribose on Insulin and Blood Glucose: A
Chronological Examination (2003).
14. FALK, Darin J., HEELAN, Kate A., THYFAULT, John P., et al. Effects of effervescent creatine, ribose, and glutamine supplementation on muscular strength, muscular endurance, and body composition. The Journal of Strength & Conditioning Research, 2003, vol. 17, no. 4, p. 810-816.
15. BERARDI, John M. and ZIEGENFUSS, Tim N. Effects of ribose supplementation on repeated sprint performance in men. The Journal of Strength & Conditioning Research, 2003, vol. 17, no. 1, p. 47-52.
16. BRAULT, Jeffrey J. and TERJUNG, Ronald L. Purine salvage to adenine nucleotides in different skeletal muscle fiber types. Journal of applied physiology, 2001, vol. 91, no. 1, p. 231-238.
17. HELLSTEN-WESTING, YLVA, NORMAN, BARBARA, BALSOM, PAUL D., et al. Decreased remaining levels of adenine nucleotides in human skeletal muscle after high-intensity training. Journal of Applied Physiology, 1993, vol. 74, no. 5, p. 2523-2528;
18. GROSS, M., KORMANN, B., and ZÖLLNER, N. Ribose administration during exercise: effects on substrates and products of energy metabolism in healthy subjects and a patient with myoadenylate deaminase deficiency. Klinische Wochenschrift, 1991, vol. 69, p. 151-155.
19. WAGNER, DR, GRESSER, U., and ZÖLLNER, N. Effects of oral ribose on muscle metabolism during bicycle ergometer in AMPD-deficient patients. Annals of nutrition and metabolism, 1991, vol. 35, no. 5, p. 297-302.
20. GROSS, M., REITER, S., and ZÖLLNER, N. Metabolism of D-ribose administered continuously to healthy persons and to patients with myoadenylate deaminase deficiency. Klinische Wochenschrift, 1989, vol. 67, p. 1205-1213.
21. Bioenergy Life Science, Inc. Online brochure, Increased NAD,ATP and GSH., 2020, https://bioenergylifescience.fr/riagev/
22. Bioenergy Life Science, Inc. Online brochure, Announcing the Next Generation in Skin Health Technology, 2021, https://bioenergylifescience.fr/riagev/
23. American Preclinical Services, Minneapolis, MN; Alex Xue, PhD, Bioenergy Life Science, Inc., Minneapolis, MN. Pharmacodynamics Study Summary of RiaGev™, https://bioenergylifescience.fr/riagev/
24. Bioenergy Life Science, Inc. (accessed 11.07.2024) https://bioenergylifescience.fr/riagev/
Ceramosides™
25. CHEN, Chun-yu, ZHANG, Jia-Qi, LI, Li, et al. Advanced glycation end products in the skin: Molecular mechanisms, methods of measurement, and inhibitory pathways. Frontiers in Medicine, 2022, vol. 9, p. 837222.
26. Seppic. Online study brochure. CERAMOSIDES™ Youthful and hydrated skin from within. 2023, https://www.seppic.com/fr
27. Seppic. Online study brochure. CERAMOSIDES™ Hair growth and strength from the inside out. 2023, https://www.seppic.com/fr
28. BIZOT, Valérie, CESTONE, Enza, MICHELOTTI, Angela, et al. Improving skin hydration and age-related symptoms by oral administration of wheat glucosylceramides and digalactosyl diglycerides: a human clinical study. Cosmetics, 2017, vol. 4, no. 4, p. 37.
29. KERN, Catherine, DUDONNÉ, Stéphanie, and GARCIA, Christine. Dietary supplementation with a wheat polar lipid complex improves skin conditions in women with dry skin and mild-to-moderate skin aging. Journal of Cosmetic Dermatology, 2024, vol. 23, no. 4, p. 1320-1330.
30. DUDONNÉ, Stéphanie, KERN, Catherine, and GARCIA, Christine. Efficacy of a wheat polar lipid complex in reducing hair loss and improving hair growth in healthy women: A randomized, double‐blind, placebo‐controlled clinical study. International Journal of Cosmetic Science, 2024, vol. 46, no. 2, p. 284-296.
31. MASTROCOLA, Raffaella, DAL BELLO, Federica, CENTO, Alessia S., et al. Altered hepatic sphingolipid metabolism in insulin resistant mice: Role of advanced glycation endproducts. Free Radical Biology and Medicine, 2021, vol. 169, p. 425-435.
32. MECKFESSEL, Matthew H. and BRANDT, Staci. The structure, function, and importance of ceramides in skin and their use as therapeutic agents in skin-care products. Journal of the American Academy of Dermatology, 2014, vol. 71, no. 1, p. 177-184.
33. SCHACHNER, Lawrence A., ALEXIS, Andrew F., ANDRIESSEN, Anneke, et al. Insights into acne and the skin barrier: Optimizing treatment regimens with ceramide‐containing skincare. Journal of Cosmetic Dermatology, 2023, vol. 22, no. 11, p. 2902-2909.
34. DRAELOS, Zoe Diana. The effect of ceramide-containing skin care products on eczema resolution duration. Cutis, 2008, vol. 81, no. 1, p. 87-91.
Resveratrol
35. ZHOU, Dan-Dan, LUO, Min, HUANG, Si-Yu, et al. Effects and mechanisms of resveratrol on aging and age‐related diseases. Oxidative medicine and cellular longevity, 2021, vol. 2021, no. 1, p. 9932218.
36. Evolva. Online brochure, Heart Health, 2022, https://veriteresveratrol.com/
37. Evolva. Online brochure, Blood Glucose, 2022, https://veriteresveratrol.com/
38. Evolva. Online Brochure, Eye Health, 2022, https://veriteresveratrol.com/
39. Evolva. Online brochure, Bone Health, 2022, https://veriteresveratrol.com/
40. Evolva. Online brochure, resveratrol re-imagined™, 2021, https://veriteresveratrol.com/
41. Evolva. Online brochure, Skin Health, 2022, https://veriteresveratrol.com/
42. POLJŠAK, Borut and DAHMANE, Raja. Free radicals and extrinsic skin aging. Dermatology research and practice, 2012, vol. 2012, no. 1, p. 135206.
43. PATRICIA FARRIS, M., JEAN KRUTMANN, M., YUAN-HONG LI, M., et al. Resveratrol: A unique antioxidant offering a multi-mechanistic approach for treating aging skin. J Drugs Dermatol, 2013, vol. 12, no. 12, p. 1389-1394.
44. BUONOCORE, Daniela, LAZZERETTI, Angelo, TOCABENS, Pedro, et al. Resveratrol-procyanidin blend: nutraceutical and antiaging efficacy evaluated in a placebo-controlled, double-blind study. Clinical, Cosmetic and Investigational Dermatology, 2012, p. 159-165.
45. BRITTON, Robert G., KOVOOR, Christina, and BROWN, Karen. Direct molecular targets of resveratrol: identifying key interactions to unlock complex mechanisms. Annals of the New York Academy of Sciences, 2015, vol. 1348, no. 1, p. 124-133.
46. BERNARD and BERTHON. Resveratrol: an original mechanism on tyrosinase inhibition. International journal of cosmetic science, 2000, vol. 22, no. 3, p. 219-226.
47. LEE, Taek Hwan, SEO, Jae Ok, BAEK, So-Hyeon, et al. Inhibitory effects of resveratrol on melanin synthesis in ultraviolet B-induced pigmentation in Guinea pig skin. Biomolecules & therapeutics, 2014, vol. 22, no. 1, p. 35.
48. COENYE, Tom, BRACKMAN, Gilles, RIGOLE, Petra, et al. Eradication of Propionibacterium acnes biofilms by plant extracts and putative identification of icariin, resveratrol and salidroside as active compounds. Phytomedicine, 2012, vol. 19, no. 5, p. 409-412.
49. KIM, So Young, HYUN, Moo Yeol, GO, Kyung Chan, et al. Resveratrol exerts growth inhibitory effects on human SZ95 sebocytes through the inactivation of the PI3-K/Akt pathway. International Journal of Molecular Medicine, 2015, vol. 35, no. 4, p. 1042-1050.
50. FABBROCINI, Gabriella, STAIBANO, Stefania, DE ROSA, Giuseppe, et al. Resveratrol-containing gel for the treatment of acne vulgaris: a single-blind, vehicle-controlled, pilot study. American journal of clinical dermatology, 2011, vol. 12, p. 133-141.
51. POULSEN, Morten Møller, FJELDBORG, Karen, ORNSTRUP, Marie Juul, et al. Resveratrol and inflammation: Challenges in translating pre-clinical findings to improved patient outcomes. Biochimica et Biophysica Acta (BBA)-Molecular Basis of Disease, 2015, vol. 1852, no. 6, p. 1124-1136.
52. KJÆR, Thomas Nordstrøm, THORSEN, Kasper, JESSEN, Niels, et al. Resveratrol ameliorates imiquimod-induced psoriasis-like skin inflammation in mice. PloS one, 2015, vol. 10, no. 5, p. e0126599.
53. DEARY, Ian J., CORLEY, Janie, GOW, Alan J., et al. Age-associated cognitive decline. British medical bulletin, 2009, vol. 92, no. 1, p. 135-152.
54. KIRK-SANCHEZ, Neva J. and MCGOUGH, Ellen L. Physical exercise and cognitive performance in the elderly: current perspectives. Clinical interventions in aging, 2014, p. 51-62.
55. WILLIAMS, Kristine N. and KEMPER, Susan. Interventions to reduce cognitive decline in aging. Journal of psychosocial nursing and mental health services, 2010, vol. 48, no. 5, p. 42-51.
56. 00. EVANS, Hamish Michael, HOWE, Peter Ranald Charles, and WONG, Rachel Heloise Xiwen. Clinical evaluation of effects of chronic resveratrol supplementation on cerebrovascular function, cognition, mood, physical function and general well-being in postmenopausal women—rationale and study design. Nutrients, 2016, vol. 8, no. 3, p. 150.
57. EVANS, Hamish M., HOWE, Peter RC, and WONG, Rachel HX. Effects of resveratrol on cognitive performance, mood and cerebrovascular function in post-menopausal women; a 14-week randomized placebo-controlled intervention trial. Nutrients, 2017, vol. 9, no. 1, p. 27.
58. WIGHTMAN, Emma L., HASKELL-RAMSAY, Crystal F., REAY, Jonathon L., et al. The effects of chronic trans-resveratrol supplementation on aspects of cognitive function, mood, sleep, health and cerebral blood flow in healthy, young humans. British Journal of Nutrition, 2015, vol. 114, no. 9, p. 1427-1437.
59. DEL FATTORE, Andrea, TETI, Anna, and RUCCI, Nadia. Bone cells and the mechanisms of bone remodeling. Frontiers in Bioscience-Elite, 2012, vol. 4, no. 6, p. 2302-2321.
60. 3) Ginaldi L, Di Benedetto MC and De Martinis M. Osteoporosis, inflammation and aging. Immunity & Aging 2005;2:14.
Phytocelltec™ MD NU
61. Mibelle AG Biochemistry. Online brochure, PhytoCellTec™ Md Nu Apple cell culture extract
for skin vitality, https://www.mibellebiochemistry.com/
62. BAUMANN, Julia, WANDREY, Franziska, NOWAK, Kathrin, et al. Nutritional supplementation of an apple callus extract to target epidermal aging. Journal of Food, Nutrition and Diet Science, 2024, p. 18-28.
63. Mibelle AG Biochemistry. Online brochure, miRNA Quantification in Cultured Apple Fruit Cells and Fresh Apple Fruit Tissue, https://www.mibellebiochemistry.com/
64. SCHMID, D., SCHÜRCH, C., BLUM, P., et al. Plant Stem Cell Extract for Longevity of Skin and Hair. SOFW Journal-Seifen Ole Fette Wachse, 2011, vol. 137, no. 5, p. 30.
65. SCHIRMER, Cedric, EIBL, Regine, MASCHKE, Rüdiger W., et al. Single‐use Technology for the Production of Cellular Agricultural Products: Where are We Today?. Chemie Ingenieur Technik, 2022, vol. 94, no. 12, p. 2018-2025.
66. GOLDFADEN, GARY. Apple Stem CellS Offer Hope For.
67. PRHAL, Jelena, MILIĆ, Jela, KRAJIŠNIK, Danina, et al. Properties and use of plant stem cells in cosmetic products. Arhiv za farmaciju, 2014, vol. 64, no. 1, p. 26-37.
Nutroxsun™
68. Nutroxun™, Grapefruit and Rosemary Extract Health Benefits, accessed 11.07.2024, https://www.elementa-ingredients.com/fr/ingredient/nutroxsun-solution-naturelle-protection-sunaire
69. NOBILE, Vincenzo, MICHELOTTI, Angela, CESTONE, Enza, et al. Skin photoprotective and antiaging effects of a combination of rosemary (Rosmarinus officinalis) and grapefruit (Citrus paradisi) polyphenols. Food & nutrition research, 2016, vol. 60, no. 1, p. 31871.
70. LI POMI, Federica, PAPA, Vincenzo, BORGIA, Francesco, et al. Rosmarinus officinalis and skin: antioxidant activity and possible therapeutic role in cutaneous diseases. Antioxidants, 2023, vol. 12, no. 3, p. 680.
71. INCE, Bilsev, YILDIRIM, Alpagan Mustafa, OKUR, Mehmet Ihsan, et al. Effects of Rosmarinus officinalis on the survivability of random-patterned skin flaps: an experimental study. Journal of plastic surgery and hand surgery, 2015, vol. 49, no. 2, p. 83-87.
72. TAKAYAMA, Katia S., MONTEIRO, Mariana C., SAITO, Priscila, et al. Rosmarinus officinalis extract-loaded emulgel prevents UVB irradiation damage to the skin. Anais da Academia Brasileira de Ciências, 2022, vol. 94, no. 4, p. e20201058.
73. İNCE, Bilsev, BILGEN, Fatma, GÜNDEŞLIOĞLU, Ayşe Özlem, et al. Use of systemic rosmarinus officinalis to enhance the survival of random-pattern skin flaps. Balkan medical journal, 2016, vol. 33, no. 6, p. 645-651.
74. MAO, Feng, WU, Zhongxiao, SHEN, Yanna, et al. Regulatory mechanism of rosemary extract (Rosmarinus officinalis) on human skin fibroblasts during ultraviolet A photoaging. Iranian Journal of Science and Technology, Transactions A: Science, 2021, vol. 45, p. 427-436.
75. NIETO, Gema, ROS, Gaspar, and CASTILLO, Julián. Antioxidant and antimicrobial properties of rosemary (Rosmarinus officinalis, L.): A review. Medicines, 2018, vol. 5, no. 3, p. 98.
76. CHEUNG, Susan and TAI, Joseph. Anti-proliferative and antioxidant properties of rosemary Rosmarinus officinalis. Oncology reports, 2007, vol. 17, no. 6, p. 1525-1531.
77. ETTER, Selma C. Rosmarinus officinalis as an antioxidant. Journal of herbs, spices & medicinal plants, 2005, vol. 11, no. 1-2, p. 121-159.
78. HUSSAIN, Abdullah Ijaz, ANWAR, Farooq, CHATHA, Shahzad Ali Shahid, et al. Rosmarinus officinalis essential oil: antiproliferative, antioxidant and antibacterial activities. Brazilian Journal of Microbiology, 2010, vol. 41, p. 1070-1078.
79. GARBARINO, Juan Antonio, TRONCOSO, Nicolás, DELPIANO, Pia, et al. Antioxidant activity analysis for the selection of Rosmarinus officinalis L. Natural Product Communications, 2006, vol. 1, no. 12, p. 1934578X0600101210.
80. LI POMI, Federica, PAPA, Vincenzo, BORGIA, Francesco, et al. Rosmarinus officinalis and skin: antioxidant activity and possible therapeutic role in cutaneous diseases. Antioxidants, 2023, vol. 12, no. 3, p. 680.
81. JORDÁN, Maria J., LAX, Vanesa, ROTA, Maria C., et al. Effect of the phenological stage on the chemical composition, and antimicrobial and antioxidant properties of Rosmarinus officinalis L essential oil and its polyphenolic extract. Industrial crops and products, 2013, vol. 48, p. 144-152.
82. CHIANG, Hsiu‐Mei, LIN, Jen‐Wen, HSIAO, Pei‐Ling, et al. Hydrolysates of citrus plants stimulate melanogenesis protecting against UV‐induced dermal damage. Phytotherapy Research, 2011, vol. 25, no. 4, p. 569-576.
83. ALRASHEID, Ayat Ahmed, MOHAMED, Alaa Abdulmoneim, MOHIELDIN, Einas Gamal, et al. Phytochemical investigation and assessment of antimicrobial, anti-inflammatory and antioxidant activities of Sudanese Citrus paradisi peel extract. Journal of Pharmacognosy and Phytotherapy, 2019, vol. 11, no. 1, p. 1-8.
84. SICARI, V., PELLICANÒ, TM, GIUFFRÈ, AM, et al. Physical chemical properties and antioxidant capacities of grapefruit juice (Citrus paradisi) extracted from two different varieties. International Food Research Journal, 2018, vol. 25, no. 5.
85. SEBGHATOLLAHI, Zahra, GHANADIAN, Mustafa, AGARWAL, Pooja, et al. Citrus flavonoids: Biological activities, implementation in skin health, and topical applications: A Review. ACS Food Science & Technology, 2022, vol. 2, no. 9, p. 1417-1432.
86. LUKITANINGSIH, Endang, NUR, Syamsu, QONITHAH, Fadilah, et al. In vitro anti-wrinkle and tyrosinase inhibitory activities of grapefruit peel and strawberry extracts. Majalah Obat Traditional, 2020, vol. 25, no. 3, p. 182-189.
87. WEST, Brett J., DENG, Shixin, PALU, Afa Kehaati, et al. Vitamin C, grape seed extract and citrus bioflavonoids protect the skin against photoaging: a review. Journal of Biosciences and Medicines, 2020, vol. 8, no. 12, p. 116.
Caviar® Biotec (CAVIAR PROTEIN)
88. PARK, Jeongjin, KIM, Dakyung, LEE, Minhee, et al. Enzyme-treated caviar prevents UVB irradiation-induced skin photoaging. Marine Drugs, 2022, vol. 20, no. 11, p. 685.
89. LEE, Kyung-Eun, NHO, Youn-Hwa, YUN, Seok Kyun, et al. Caviar extract and its constituent DHA inhibits UVB-irradiated skin aging by inducing adiponectin production. International journal of molecular sciences, 2020, vol. 21, no. 9, p. 3383.
90. NA, Gwi Hwan, KIM, SukJin, JUNG, Hyun Mook, et al. Skin Anti-Aging Efficacy of Enzyme-Treated Supercritical Caviar Extract: A Randomized, Double-Blind, Placebo-Controlled Clinical Trial. Nutrients, 2023, vol. 16, no. 1, p. 137.
91. MAROTTA, Francesco, POLIMENI, Ascanio, SOLIMENE, Umberto, et al. Beneficial modulation from a high-purity caviar-derived homogenate on chronological skin aging. Rejuvenation Research, 2012, vol. 15, no. 2, p. 174-177.
92. ZDROJEWICZ, Zygmunt, WRÓBLEWSKA, Magdalena, TOMASZEWSKI, Łukasz, et al. Caviar–luxury or health?. Medycyna Rodzinna, 2016.
93. IMBERT, Isabelle, BOTTO, Jean‐Marie, FARRA, Claude D., et al. Modulation of telomere binding proteins: a future area of research for skin protection and anti‐aging targets. Journal of Cosmetic Dermatology, 2012, vol. 11, no. 2, p. 162-166.
94. YAGI, Masayuki and YONEI, Yoshikazu. Glycative stress and anti-aging: 7. Glycative stress and skin aging. Glycative Stress Res, 2018, vol. 5, no. 1, p. 50-54.
95. MASAKI, Hitoshi. Role of antioxidants in the skin: anti-aging effects. Journal of dermatological science, 2010, vol. 58, no. 2, p. 85-90.
96. YOO, Mi Ae, SONG, Young Keun, JANG, Hyein, et al. Profiling of skin anti-aging related proteins in human dermal fibroblasts by decursin in Angelica gigas Nakai. Korean Journal of Chemical Engineering, 2011, vol. 28, p. 880-885.
97. HAMEURY, Sebastien, BORDERIE, Laurent, MONNEUSE, Jean‐Marc, et al. Prediction of skin anti‐aging clinical benefits of an association of ingredients from marine and maritime origins: ex vivo evaluation using a label‐free quantitative proteomic and customized data processing approach. Journal of Cosmetic Dermatology, 2019, vol. 18, no. 1, p. 355-370.
OTHER INGREDIENTS
D-RIBOSE
98. FLANIGAN, Richard, MACCARTER, Dean, SHECTERLE, Linda M., et al. D-ribose aids fatigue in aging adults. The Journal Of Alternative And Complementary Medicine, 2010, vol. 16, no. 5, p. 529.
99. ZHANG, Zhengang and FENG, WANG Effects of aerobic exercise combined with D-ribose supplementation on anti-fatigue and anti-oxidation in mice. 2022.
100. SHECTERLE, Linda M. and ST. CYR, John A. Dermal benefits of topical D-ribose. Clinical, Cosmetic and Investigational Dermatology, 2009, p. 151-152.
101. WEI, Yan, HAN, Chan Shuai, ZHOU, Jun, et al. D-ribose in glycation and protein aggregation. Biochimica et Biophysica Acta (BBA)-General Subjects, 2012, vol. 1820, no. 4, p. 488-494.
102. HAN, Chanshuai, LU, Yang, WEI, Yan, et al. D-ribose induces cellular protein glycation and impairs mouse spatial cognition. PLoS One, 2011, vol. 6, no. 9, p. e24623.
103. XUE, Yongquan, SHAMP, Trisha, NAGANA GOWDA, GA, et al. A combination of nicotinamide and D-ribose (RiaGev) is safe and effective to increase NAD+ metabolome in healthy middle-aged adults: a randomized, triple-blind, placebo-controlled, cross-over pilot clinical trial. Nutrients, 2022, vol. 14, no. 11, p. 2219.
104. PAULY, Daniel F. and PEPINE, Carl J. D-Ribose as a supplement for cardiac energy metabolism. journal of Cardiovascular Pharmacology and Therapeutics, 2000, vol. 5, no. 4, p. 249-258.
105. SEIFERT, John G., BRUMET, Allison, and ST CYR, John A. The influence of D-ribose ingestion and fitness level on performance and recovery. Journal of the International Society of Sports Nutrition, 2017, vol. 14, no. 1, p. 47.
106. MAHONEY, Diane E., HIEBERT, John B., THIMMESCH, Amanda, et al. Understanding D-ribose and mitochondrial function. Advances in bioscience and clinical medicine, 2018, vol. 6, no. 1, p. 1.
107. CAO, Wei, QIU, Junqiang, CAI, Tianwei, et al. Effect of D-ribose supplementation on delayed onset muscle soreness induced by plyometric exercise in college students. Journal of the International Society of Sports Nutrition, 2020, vol. 17, p. 1-9.
108. ADDIS, Paul, SHECTERLE, Linda M., and A. ST. CYR, John. Cellular protection during oxidative stress: a potential role for D-ribose and antioxidants. Journal of Dietary Supplements, 2012, vol. 9, no. 3, p. 178-182.
109. TEITELBAUM, Jacob E., JOHNSON, Clarence, and CYR, John St. The use of D-ribose in chronic fatigue syndrome and fibromyalgia: a pilot study. Journal of Alternative & Complementary Medicine, 2006, vol. 12, no. 9, p. 857-862.
110. SALTMAN, Adam E. D-ribose-l-cysteine supplementation enhances wound healing in a rodent model. The American Journal of Surgery, 2015, vol. 210, no. 1, p. 153-158.
ASCORBIC ACID (VITAMIN C)
111. MEISTER, Alton. On the antioxidant effects of ascorbic acid and glutathione. Biochemical pharmacology, 1992, vol. 44, no. 10, p. 1905-1915.
112. LEE, Kun Kook and CHOI, Jung‐Do. The effects of Areca catechu L extract on anti‐aging. International journal of cosmetic science, 1999, vol. 21, no. 4, p. 285-295.
00. BONTÉ, Frédéric. Skin care products. Chemical news, 2008, no. 323-324, p. 52.
113. HADDADI, Hayat. Determination of the antioxidant activity of some fruits. 2005. Doctoral thesis. Béjaia, Abderrahmane Mira University. Faculty of Natural and Life Sciences.
114. PULLAR, Juliet M., CARR, Anitra C., and VISSERS, Margreet. The roles of vitamin C in skin health. Nutrients, 2017, vol. 9, no. 8, p. 866.
115. DARR, D., COMBS, S., DUNSTON, S., et al. Topical vitamin C protects porcine skin from ultraviolet radiation‐induced damage. British Journal of Dermatology, 1992, vol. 127, no. 3, p. 247-253.
116. CARR, Anitra C. and MAGGINI, Silvia. Vitamin C and immune function. Nutrients, 2017, vol. 9, no. 11, p. 1211.
117. CHAN, Alvin C. Partners in defense, vitamin E and vitamin C. Canadian journal of physiology and pharmacology, 1993, vol. 71, no. 9, p. 725-731.
118. BUNDESEN, Herman N., ARON, Hans CS, GREENEBAUM, Regina S., et al. THE DETOXIFYING ACTION OF VITAMIN C (ASCORBIC ACID) IN ARSENICAL THERAPY: ASCORBIC ACID AS A PREVENTIVE OF REACTIONS OF HUMAN SKIN TO NEOARSPHENAMINE. Journal of the American Medical Association, 1941, vol. 117, no. 20, p. 1692-1695.
119. BOYERA, N., GALEY, I., and BERNARD, BA Effect of vitamin C and its derivatives on collagen synthesis and cross‐linking by normal human fibroblasts. International journal of cosmetic science, 1998, vol. 20, no. 3, p. 151-158.
120. CHEN, Juanjuan, LIU, Yang, ZHAO, Zhao, et al. Oxidative stress in the skin: Impact and related protection. International Journal of Cosmetic Science, 2021, vol. 43, no. 5, p. 495-509.
121. WEST, Brett J., DENG, Shixin, PALU, Afa Kehaati, et al. Vitamin C, grape seed extract and citrus bioflavonoids protect the skin against photoaging: a review. Journal of Biosciences and Medicines, 2020, vol. 8, no. 12, p. 116.
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L-SELENOMETHIONINE
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GLYCINE
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L-CARNOSINE
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GRAPE SEEDS
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ORGANIC GRAPE JUICE CONCENTRATE
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The claims presented in this document are based on rigorous scientific evidence and comply with current regulations regarding food supplements. This bibliography aims to ensure the transparency and legal compliance of the information provided on Hectyl JVCE® FORMULA. The information contained in this bibliography has been collected and presented in accordance with current regulatory requirements, including Regulation (EC) No. 1924/2006 on nutrition and health claims made on foods. The statements about this product are not intended to diagnose, treat, cure, or prevent any disease. It is important to remember that food supplements should not be used as a substitute for a varied and balanced diet and a healthy lifestyle. If in doubt, please consult a healthcare professional.
Updated on 07/17/2024